TY - JOUR
T1 - A single-arm pilot of a web-based intervention to improve itch-related quality of life
AU - Heckman, C. J.
AU - Riley, M.
AU - Niu, Z.
AU - Lu, S. E.
AU - Valdes-Rodriguez, R.
AU - Yosipovitch, G.
N1 - Funding Information:
The authors thank Kristen Sorice, Melissa Auerbach, Christine Huang, Shiju Daniel, Baichen Xu and Anna Mitarotondo for their assistance with website development and data management. Permission to use the MMAS scales is required. Reproduction and distribution of the MMAS is protected by US copyright laws. A license agreement to use the scale is available from: Donald E. Morisky, ScD, ScM, MSPH, Professor, Department of Community Health Sciences, UCLA School of Public Health, 650 Charles E. Young Drive South, Los Angeles, CA 90095-1772, dmorisky@ucla.edu.
Publisher Copyright:
© 2021 European Academy of Dermatology and Venereology.
PY - 2022/1
Y1 - 2022/1
N2 - Background: Many patients with chronic itch and atopic dermatitis (AD) or psoriasis do not receive/use available medical and psychosocial treatments properly due to system, provider and/or patient factors. Objective: An educational website (ITCH-RELIEF) to improve itch-related quality of life (QoL) for adults with AD or psoriasis and chronic itch was developed and assessed. ITCH RELIEF stands for Interactive Toolbox of Comprehensive Health Resources to Enhance Living with Itch – Educational Facilitation (for Adults). Methods: Single-arm pre- and post-test design with 1-month follow-up (N = 137 at baseline). Results: There was statistically and clinically significant improvement in the primary outcome of itch-related QoL impairment as assessed by the ItchyQoL from baseline [M = 78.9, 95% confidence interval (CI) = 75.9, 81.9] to follow up (M = 75.4, CI = 72.4, 78.5), P = 0.007, as well as statistically significant improvement in several itch-related secondary outcomes (all Ps < 0.05). Conclusions: This study demonstrated initial effectiveness of an online intervention to improve itch-related QoL among individuals with AD or psoriasis and chronic itch. Future studies should address limitations by randomizing more heterogeneous participants, utilizing a longer follow-up and assessing medication use.
AB - Background: Many patients with chronic itch and atopic dermatitis (AD) or psoriasis do not receive/use available medical and psychosocial treatments properly due to system, provider and/or patient factors. Objective: An educational website (ITCH-RELIEF) to improve itch-related quality of life (QoL) for adults with AD or psoriasis and chronic itch was developed and assessed. ITCH RELIEF stands for Interactive Toolbox of Comprehensive Health Resources to Enhance Living with Itch – Educational Facilitation (for Adults). Methods: Single-arm pre- and post-test design with 1-month follow-up (N = 137 at baseline). Results: There was statistically and clinically significant improvement in the primary outcome of itch-related QoL impairment as assessed by the ItchyQoL from baseline [M = 78.9, 95% confidence interval (CI) = 75.9, 81.9] to follow up (M = 75.4, CI = 72.4, 78.5), P = 0.007, as well as statistically significant improvement in several itch-related secondary outcomes (all Ps < 0.05). Conclusions: This study demonstrated initial effectiveness of an online intervention to improve itch-related QoL among individuals with AD or psoriasis and chronic itch. Future studies should address limitations by randomizing more heterogeneous participants, utilizing a longer follow-up and assessing medication use.
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U2 - 10.1111/jdv.17686
DO - 10.1111/jdv.17686
M3 - Article
C2 - 34549834
AN - SCOPUS:85116330778
SN - 0926-9959
VL - 36
SP - 108
EP - 112
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
IS - 1
ER -