ACTION OF HYPERTHERMIA ON GENE EXPRESSION IN FRIEND ERYTHROLEUKEMIA CELLS BY DIMETHYL SULFOXIDE OR X-RAYS.

G. P. RAAPHORST; E. I. AZZAM; M. EINSPENNER; D. EWING; J. BORSA

ACTION OF HYPERTHERMIA ON GENE EXPRESSION IN FRIEND ERYTHROLEUKEMIA CELLS BY DIMETHYL SULFOXIDE OR X-RAYS.

G. P. RAAPHORST, E. I. AZZAM, M. EINSPENNER, D. EWING, J. BORSA

Research output: Contribution to journal › Article › peer-review

Abstract

THE EFFECT OF HEAT ON GENE CONTROL AND ON CELL KILLING BY X-RAYS OR DIMETHYL SULFOXIDE (DMSO) WAS STUDIED IN CULTURED FRIEND ERYTHROLEUKEMIA CELLS (FELC). FELC ARE VERY SENSITIVE TO HEAT AND X-RAYS IN TERMS OF SURVIVAL, AS MEASURED BY THE COLONY-FORMING ASSAY. HEAT INACTIVATION KINETICS ARE SIMILARFOR FELC AND CHINESE HAMSTER CELLS. THERMAL ENHANCEMENT OF CELL INACTIVATION BY IRRADIATION WAS OBSERVED AT 42. 0 AND 45. 0 D. C, AND INCREASED AS A FUNCTION OF HEATING TIME. THE SIMULTANEOUS APPLICATION OF HEAT AND X-RAYS HAD A GREATER EFFECT IN TERMS OF CELL INACTIVATION.

Original language	English (US)
Journal	At Energy Can Ltd Rep
State	Published - 1982
Externally published	Yes

All Science Journal Classification (ASJC) codes

Nuclear and High Energy Physics
Nuclear Energy and Engineering

Cite this

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title = "ACTION OF HYPERTHERMIA ON GENE EXPRESSION IN FRIEND ERYTHROLEUKEMIA CELLS BY DIMETHYL SULFOXIDE OR X-RAYS.",

abstract = "THE EFFECT OF HEAT ON GENE CONTROL AND ON CELL KILLING BY X-RAYS OR DIMETHYL SULFOXIDE (DMSO) WAS STUDIED IN CULTURED FRIEND ERYTHROLEUKEMIA CELLS (FELC). FELC ARE VERY SENSITIVE TO HEAT AND X-RAYS IN TERMS OF SURVIVAL, AS MEASURED BY THE COLONY-FORMING ASSAY. HEAT INACTIVATION KINETICS ARE SIMILARFOR FELC AND CHINESE HAMSTER CELLS. THERMAL ENHANCEMENT OF CELL INACTIVATION BY IRRADIATION WAS OBSERVED AT 42. 0 AND 45. 0 D. C, AND INCREASED AS A FUNCTION OF HEATING TIME. THE SIMULTANEOUS APPLICATION OF HEAT AND X-RAYS HAD A GREATER EFFECT IN TERMS OF CELL INACTIVATION.",

author = "RAAPHORST, {G. P.} and AZZAM, {E. I.} and M. EINSPENNER and D. EWING and J. BORSA",

year = "1982",

language = "English (US)",

journal = "At Energy Can Ltd Rep",

issn = "0067-0383",

publisher = "Atomic Energy Of Canada Ltd.",

}

TY - JOUR

T1 - ACTION OF HYPERTHERMIA ON GENE EXPRESSION IN FRIEND ERYTHROLEUKEMIA CELLS BY DIMETHYL SULFOXIDE OR X-RAYS.

AU - RAAPHORST, G. P.

AU - AZZAM, E. I.

AU - EINSPENNER, M.

AU - EWING, D.

AU - BORSA, J.

PY - 1982

Y1 - 1982

N2 - THE EFFECT OF HEAT ON GENE CONTROL AND ON CELL KILLING BY X-RAYS OR DIMETHYL SULFOXIDE (DMSO) WAS STUDIED IN CULTURED FRIEND ERYTHROLEUKEMIA CELLS (FELC). FELC ARE VERY SENSITIVE TO HEAT AND X-RAYS IN TERMS OF SURVIVAL, AS MEASURED BY THE COLONY-FORMING ASSAY. HEAT INACTIVATION KINETICS ARE SIMILARFOR FELC AND CHINESE HAMSTER CELLS. THERMAL ENHANCEMENT OF CELL INACTIVATION BY IRRADIATION WAS OBSERVED AT 42. 0 AND 45. 0 D. C, AND INCREASED AS A FUNCTION OF HEATING TIME. THE SIMULTANEOUS APPLICATION OF HEAT AND X-RAYS HAD A GREATER EFFECT IN TERMS OF CELL INACTIVATION.

AB - THE EFFECT OF HEAT ON GENE CONTROL AND ON CELL KILLING BY X-RAYS OR DIMETHYL SULFOXIDE (DMSO) WAS STUDIED IN CULTURED FRIEND ERYTHROLEUKEMIA CELLS (FELC). FELC ARE VERY SENSITIVE TO HEAT AND X-RAYS IN TERMS OF SURVIVAL, AS MEASURED BY THE COLONY-FORMING ASSAY. HEAT INACTIVATION KINETICS ARE SIMILARFOR FELC AND CHINESE HAMSTER CELLS. THERMAL ENHANCEMENT OF CELL INACTIVATION BY IRRADIATION WAS OBSERVED AT 42. 0 AND 45. 0 D. C, AND INCREASED AS A FUNCTION OF HEATING TIME. THE SIMULTANEOUS APPLICATION OF HEAT AND X-RAYS HAD A GREATER EFFECT IN TERMS OF CELL INACTIVATION.

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SN - 0067-0383

JO - At Energy Can Ltd Rep

JF - At Energy Can Ltd Rep

ER -

ACTION OF HYPERTHERMIA ON GENE EXPRESSION IN FRIEND ERYTHROLEUKEMIA CELLS BY DIMETHYL SULFOXIDE OR X-RAYS.

Abstract

All Science Journal Classification (ASJC) codes

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