Zhao et al. show that meiosis genes facilitate ploidy reduction in the global fungal pathogen Cryptococcus neoformans, and they are activated during infection. Progeny isolated from the host that have meiotic genes activated show increased resistance to specific genotoxic stress, indicating the occurrence of meiosis may empower adaptative mutations.
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)
- phenotypic diversity
- ploidy reduction
- unisexual reproduction