Adherence to antiretroviral therapy in pediatric patients with human immunodeficiency virus (HIV-1)

G. Burack Gail; Sunanda Gaur; Roseann Marone; Anna Petrova

doi:10.1016/j.pedn.2009.07.002

Adherence to antiretroviral therapy in pediatric patients with human immunodeficiency virus (HIV-1)

G. Burack Gail, Sunanda Gaur, Roseann Marone, Anna Petrova

Robert Wood Johnson Medical School (RWJMS), Pediatrics, Division of Infectious Diseases

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The evaluation of HIV treatment adherence is essential to manage the development of resistant mutations, treatment failure, and disease progression in patients with HIV-1 infection; however, none of the commonly used measures of treatment adherence have been found to be accurate. The objective of this study was to evaluate three treatment adherence measures (caregiver reports, pharmacy refill, and appointment maintenance data) in association with viral load suppression in pediatric patients with HIV-1 infection. Although viral suppression was not found to be significantly associated with adherence defined by any single measure, treatment adherence could be predicted if all three measures were in agreement.

Original language	English (US)
Pages (from-to)	500-504
Number of pages	5
Journal	Journal of pediatric nursing
Volume	25
Issue number	6
DOIs	https://doi.org/10.1016/j.pedn.2009.07.002
State	Published - Dec 2010

All Science Journal Classification (ASJC) codes

Pediatrics

Keywords

Adherence
Antiretroviral therapy
Children
HIV

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10.1016/j.pedn.2009.07.002

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title = "Adherence to antiretroviral therapy in pediatric patients with human immunodeficiency virus (HIV-1)",

abstract = "The evaluation of HIV treatment adherence is essential to manage the development of resistant mutations, treatment failure, and disease progression in patients with HIV-1 infection; however, none of the commonly used measures of treatment adherence have been found to be accurate. The objective of this study was to evaluate three treatment adherence measures (caregiver reports, pharmacy refill, and appointment maintenance data) in association with viral load suppression in pediatric patients with HIV-1 infection. Although viral suppression was not found to be significantly associated with adherence defined by any single measure, treatment adherence could be predicted if all three measures were in agreement.",

keywords = "Adherence, Antiretroviral therapy, Children, HIV",

author = "{Burack Gail}, G. and Sunanda Gaur and Roseann Marone and Anna Petrova",

note = "Funding Information: The authors have received no extramural funding or commercial financial support. This article has not been previously presented. ",

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AU - Marone, Roseann

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N1 - Funding Information: The authors have received no extramural funding or commercial financial support. This article has not been previously presented.

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AB - The evaluation of HIV treatment adherence is essential to manage the development of resistant mutations, treatment failure, and disease progression in patients with HIV-1 infection; however, none of the commonly used measures of treatment adherence have been found to be accurate. The objective of this study was to evaluate three treatment adherence measures (caregiver reports, pharmacy refill, and appointment maintenance data) in association with viral load suppression in pediatric patients with HIV-1 infection. Although viral suppression was not found to be significantly associated with adherence defined by any single measure, treatment adherence could be predicted if all three measures were in agreement.

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Adherence to antiretroviral therapy in pediatric patients with human immunodeficiency virus (HIV-1)

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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