Adherence to antiretroviral therapy in pediatric patients with human immunodeficiency virus (HIV-1)

G. Burack Gail, Sunanda Gaur, Roseann Marone, Anna Petrova

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

The evaluation of HIV treatment adherence is essential to manage the development of resistant mutations, treatment failure, and disease progression in patients with HIV-1 infection; however, none of the commonly used measures of treatment adherence have been found to be accurate. The objective of this study was to evaluate three treatment adherence measures (caregiver reports, pharmacy refill, and appointment maintenance data) in association with viral load suppression in pediatric patients with HIV-1 infection. Although viral suppression was not found to be significantly associated with adherence defined by any single measure, treatment adherence could be predicted if all three measures were in agreement.

Original languageEnglish (US)
Pages (from-to)500-504
Number of pages5
JournalJournal of pediatric nursing
Volume25
Issue number6
DOIs
StatePublished - Dec 2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics

Keywords

  • Adherence
  • Antiretroviral therapy
  • Children
  • HIV

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