Alcohol consumption and endometrial cancer: Some unresolved issues

Elisa Bandera, Lawrence H. Kushi, Sara H. Olson, Wendy Y. Chen, Paola Muti

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The role of hormonal factors, in particular unopposed estrogens, on endometrial cancer occurrence is well established. Progesterone deficiency has also been suggested as a possible risk factor. Alcohol use has been shown to be associated with elevated estrogen levels and reduced progesterone. Epidemiologic studies, however, have not offered much support for a positive association between alcohol intake and endometrial cancer, with results generally indicating no association or suggesting an inverse relationship with endometrial cancer. However, certain methodologic limitations, such as small sample size, limited range of alcohol intake, and confounding may have explained those findings. Moreover, there are some unexplored aspects of the possible effect of alcohol, such as the possible interaction with use of exogenous estrogens, and other factors, that need clarification.

Original languageEnglish (US)
Pages (from-to)24-29
Number of pages6
JournalNutrition and Cancer
Volume45
Issue number1
DOIs
StatePublished - Jan 1 2003

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Endometrial Neoplasms
Alcohol Drinking
Alcohols
Estrogens
Progesterone
Sample Size
Epidemiologic Studies

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Oncology
  • Nutrition and Dietetics
  • Cancer Research

Cite this

Bandera, Elisa ; Kushi, Lawrence H. ; Olson, Sara H. ; Chen, Wendy Y. ; Muti, Paola. / Alcohol consumption and endometrial cancer : Some unresolved issues. In: Nutrition and Cancer. 2003 ; Vol. 45, No. 1. pp. 24-29.
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Alcohol consumption and endometrial cancer : Some unresolved issues. / Bandera, Elisa; Kushi, Lawrence H.; Olson, Sara H.; Chen, Wendy Y.; Muti, Paola.

In: Nutrition and Cancer, Vol. 45, No. 1, 01.01.2003, p. 24-29.

Research output: Contribution to journalArticle

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