Alcohol consumption as a cofactor in the progression of HIV infection and AIDS

Lili Penkower, Mary Amanda Dew, Lawrence Kingsley, Susan Y. Zhou, Constantine G. Lyketsos, Jerry Wesch, J. Walton Senterfitt, Donald R. Hoover, James T. Becker

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Alcohol consumption as a cofactor in the progression of HIV infection was examined in 1446 homosexual and bisexual HIV + men enrolled in the Multicenter AIDS Cohort Study who had a minimum of three visits. Two measures of drinking were employed: initial level, and pattern during the study period. Outcome measures included AIDS-related symptoms and AIDS diagnosis. Level of drinking at entry to the study was not significantly associated with either AIDS-related symptoms at final visit or with AIDS diagnosis. However, men who decreased drinking were more likely to report thrush, fatigue, weight loss, and diarrhea at their final visit. Most likely, these men decreased drinking as a result of failing health, not because their drinking pattern influenced symptom onset. These data support earlier reports that found no relationship between alcohol consumption and progression to AIDS.

Original languageEnglish (US)
Pages (from-to)547-552
Number of pages6
JournalAlcohol
Volume12
Issue number6
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Biochemistry
  • Toxicology
  • Neurology
  • Behavioral Neuroscience

Keywords

  • AIDS
  • Alcohol
  • HIV

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    Penkower, L., Dew, M. A., Kingsley, L., Zhou, S. Y., Lyketsos, C. G., Wesch, J., Senterfitt, J. W., Hoover, D. R., & Becker, J. T. (1995). Alcohol consumption as a cofactor in the progression of HIV infection and AIDS. Alcohol, 12(6), 547-552. https://doi.org/10.1016/0741-8329(95)00042-9