Amidine pseudodisaccharides

Spencer Knapp; Yun H. Choe; Eileen Reilly

doi:10.1016/0040-4039(93)88054-M

Amidine pseudodisaccharides

Spencer Knapp, Yun H. Choe, Eileen Reilly

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The synthesis of several aminoglucopyranose-based amidine pseudodisaccharides is described. They may serve as glycosidase inhibitors by virtue of structural similarities to both the reducing and non-reducing pyranose units involved in glycolysis.

Original language	English (US)
Pages (from-to)	4443-4446
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	28
DOIs	https://doi.org/10.1016/0040-4039(93)88054-M
State	Published - Jul 9 1993

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

Vilsmeier activation
amidine stability
glucopyranosyl cation
glycosidase inhibitors
transition state mimics

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10.1016/0040-4039(93)88054-M

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title = "Amidine pseudodisaccharides",

abstract = "The synthesis of several aminoglucopyranose-based amidine pseudodisaccharides is described. They may serve as glycosidase inhibitors by virtue of structural similarities to both the reducing and non-reducing pyranose units involved in glycolysis.",

keywords = "Vilsmeier activation, amidine stability, glucopyranosyl cation, glycosidase inhibitors, transition state mimics",

author = "Spencer Knapp and Choe, {Yun H.} and Eileen Reilly",

year = "1993",

month = jul,

day = "9",

doi = "10.1016/0040-4039(93)88054-M",

language = "English (US)",

volume = "34",

pages = "4443--4446",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "28",

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TY - JOUR

T1 - Amidine pseudodisaccharides

AU - Knapp, Spencer

AU - Choe, Yun H.

AU - Reilly, Eileen

PY - 1993/7/9

Y1 - 1993/7/9

N2 - The synthesis of several aminoglucopyranose-based amidine pseudodisaccharides is described. They may serve as glycosidase inhibitors by virtue of structural similarities to both the reducing and non-reducing pyranose units involved in glycolysis.

AB - The synthesis of several aminoglucopyranose-based amidine pseudodisaccharides is described. They may serve as glycosidase inhibitors by virtue of structural similarities to both the reducing and non-reducing pyranose units involved in glycolysis.

KW - Vilsmeier activation

KW - amidine stability

KW - glucopyranosyl cation

KW - glycosidase inhibitors

KW - transition state mimics

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UR - http://www.scopus.com/inward/citedby.url?scp=0027214717&partnerID=8YFLogxK

U2 - 10.1016/0040-4039(93)88054-M

DO - 10.1016/0040-4039(93)88054-M

M3 - Article

AN - SCOPUS:0027214717

SN - 0040-4039

VL - 34

SP - 4443

EP - 4446

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 28

ER -

Amidine pseudodisaccharides

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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