Amidine pseudodisaccharides

Spencer Knapp, Yun H. Choe, Eileen Reilly

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

The synthesis of several aminoglucopyranose-based amidine pseudodisaccharides is described. They may serve as glycosidase inhibitors by virtue of structural similarities to both the reducing and non-reducing pyranose units involved in glycolysis.

Original languageEnglish (US)
Pages (from-to)4443-4446
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number28
DOIs
StatePublished - Jul 9 1993

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Keywords

  • Vilsmeier activation
  • amidine stability
  • glucopyranosyl cation
  • glycosidase inhibitors
  • transition state mimics

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