TY - JOUR
T1 - An anonymous unlinked sero-prevalence survey of HIVHCV in an urban Emergency Department
AU - Mohammed, Debbie Y.
AU - Martin, Eugene
AU - Sadashige, Charlotte
AU - Jaker, Michael
AU - Paul, Sindy
N1 - Funding Information:
During the study period routine opt-out testing performed by HIV counselors was available to all patients. This study was approved by the Institutional Review Board at University of Medicine and Dentistry of New Jersey and the New Jersey Department of Health.
PY - 2013/12
Y1 - 2013/12
N2 - Background: In 2002, the sero-prevalence of human immunodeficiency virus-1 (HIV) in the Emergency Department (ED), University Hospital, Newark, New Jersey was 10.4%. Both HIV and hepatitis C virus (HCV) are transmitted by injection drug use (IDU) or sexual contact. However, the degree of concurrent positive HCV antibody status in HIV-infected ED patients is unknown. Objectives: In this study we determined the sero-prevalence of HIV and HIVHCV in HIV-positive patients in the ED. Study design: A cross-sectional study using an anonymous sero-prevalence survey was conducted from 7/1/2008 to 8/23/2008. Medical records were reviewed and de-identified; remnant blood specimens were also de-identified and tested for HIV antibody, and if positive, HCV antibody. Results: Of 3488 specimens, 225 (6.5%, 95% CI: 5.7-7.3%) were positive for HIV antibody. Seventy-four patients 74/225 (32.9%, 95% CI: 33.8-46.5%) were unaware of their sero-positivity. Forty percent of HIV positive patients (90/225, 95% CI: 33.8-46.5%) were HCV antibody positive. The highest seroprevalence of HIVHCV antibody was among older patients (≥45 years), and patients with positive urine toxicology and elevated liver function tests. Discussion: Given the high prevalence of HIV and HIVHCV antibody in the ED, routine testing is important for patients ≥45 years with positive urine toxicology and elevated liver function tests.
AB - Background: In 2002, the sero-prevalence of human immunodeficiency virus-1 (HIV) in the Emergency Department (ED), University Hospital, Newark, New Jersey was 10.4%. Both HIV and hepatitis C virus (HCV) are transmitted by injection drug use (IDU) or sexual contact. However, the degree of concurrent positive HCV antibody status in HIV-infected ED patients is unknown. Objectives: In this study we determined the sero-prevalence of HIV and HIVHCV in HIV-positive patients in the ED. Study design: A cross-sectional study using an anonymous sero-prevalence survey was conducted from 7/1/2008 to 8/23/2008. Medical records were reviewed and de-identified; remnant blood specimens were also de-identified and tested for HIV antibody, and if positive, HCV antibody. Results: Of 3488 specimens, 225 (6.5%, 95% CI: 5.7-7.3%) were positive for HIV antibody. Seventy-four patients 74/225 (32.9%, 95% CI: 33.8-46.5%) were unaware of their sero-positivity. Forty percent of HIV positive patients (90/225, 95% CI: 33.8-46.5%) were HCV antibody positive. The highest seroprevalence of HIVHCV antibody was among older patients (≥45 years), and patients with positive urine toxicology and elevated liver function tests. Discussion: Given the high prevalence of HIV and HIVHCV antibody in the ED, routine testing is important for patients ≥45 years with positive urine toxicology and elevated liver function tests.
KW - Anonymous unlinked sero-survey
KW - Emergency department
KW - Prevalence HIVHCV antibody
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U2 - 10.1016/j.jcv.2013.08.025
DO - 10.1016/j.jcv.2013.08.025
M3 - Article
C2 - 24342474
AN - SCOPUS:84890237899
SN - 1386-6532
VL - 58
SP - e19-e23
JO - Journal of Clinical Virology
JF - Journal of Clinical Virology
IS - SUPPL1
ER -