An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin

José M. Rivera; Mariana Martín-Hidalgo; Jean C. Rivera-Ríos

doi:10.1039/c2ob25913c

An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin

José M. Rivera, Mariana Martín-Hidalgo, Jean C. Rivera-Ríos

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments.

Original language	English (US)
Pages (from-to)	7562-7565
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	37
DOIs	https://doi.org/10.1039/c2ob25913c
State	Published - Oct 7 2012
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c2ob25913c

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title = "An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin",

abstract = "We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments.",

author = "Rivera, {Jos{\'e} M.} and Mariana Mart{\'i}n-Hidalgo and Rivera-R{\'i}os, {Jean C.}",

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AU - Rivera, José M.

AU - Martín-Hidalgo, Mariana

AU - Rivera-Ríos, Jean C.

PY - 2012/10/7

Y1 - 2012/10/7

N2 - We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments.

AB - We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments.

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JF - Organic and Biomolecular Chemistry

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ER -

An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin

Abstract

All Science Journal Classification (ASJC) codes

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