An Optical Exposé of Cortical Function

Naomi Shvedov, David J. Margolis

Research output: Contribution to journalShort surveypeer-review


Neural imaging benefits from optical access to widespread brain areas. A recent study (Ghanbari et al. Nat. Commun. 2019;10;1500) introduces See-Shell, a transparent polymer skull that reveals the entire dorsal cortex in mice. See-Shells are 3D-printed, customizable, and modifiable for combined neural recording and manipulation, offering advantages for high-resolution, multiscale measures of in vivo brain function.

Original languageEnglish (US)
Pages (from-to)511-513
Number of pages3
JournalTrends in Neurosciences
Issue number8
StatePublished - Aug 2019

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)


  • brain function
  • imaging
  • microscopy
  • neural circuits
  • plasticity
  • see-shell


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