Analysis of left ventricular wall motion based on volumetric deformable models and MRI-SPAMM

Jinah Park, Dimitri Metaxas, Leon Axel

Research output: Contribution to journalArticlepeer-review

166 Scopus citations


We present a new approach for the analysis of the left ventricular shape and motion based on the development of a new class of volumetric deformable models. We estimate the deformation and complex motion of the left ventricle (LV) in terms of a few parameters that are functions and whose values vary locally across the LV. These parameters capture the radial and longitudinal contraction, the axial twisting, and the long-axis deformation. Using Lagrangian dynamics and finite-element theory, we convert these volumetric primitives into dynamic models that deform due to forces exerted by the datapoints. We present experiments where we used magnetic tagging (MRI-SPAMM) to acquire datapoints from the LV during systole. By applying our method to MRI-SPAMM datapoints, we were able to characterize the 3-D shape and motion of the LV both locally and globally, in a clinically useful way. In addition, based on the model parameters we were able to extract quantitative differences between normal and abnormal hearts and visualize them in a way that is useful to physicians.

Original languageEnglish (US)
Pages (from-to)53-71
Number of pages19
JournalMedical Image Analysis
Issue number1
StatePublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design


  • Intuitive parameters
  • Left ventricle (LV)
  • Physics-based modelling
  • Quantitative shape and motion analysis
  • Volumetric deformable models

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