Anatomical and physiological simulation for respiratory mechanics

Jonathan Kaye, Frank P. Primiano, Dimitri Metaxas

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Injuries in trauma affect anatomical structures, indirectly affecting physiological systems through mechanical behavior and physical proximity. This paper describes the theory for and preliminary results from our approach to couple a three-dimensional (3-D) anatomical model of the chest with a physiological model of respiratory mechanics. In particular, we investigated behavior in quiet, normal breathing and in an open, sucking chest wound. We envision that our integrated simulation of respiratory anatomy and respiratory mechanics could assist students in visualizing and predicting relationships between structural-anatomical and functional-physiological changes in an interactive, 3-D environment.

Original languageEnglish (US)
Pages (from-to)164-171
Number of pages8
JournalComputer Aided Surgery
Issue number3
StatePublished - 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Radiology Nuclear Medicine and imaging


  • Anatomical simulation
  • Breathing
  • Chest model
  • Respiratory mechanics


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