Anemia and bleeding in thrombocytopenic patients

Jeffrey L. Carson; Simon J. Stanworth

doi:10.1182/blood-2017-07-795922

Anemia and bleeding in thrombocytopenic patients

Jeffrey L. Carson, Simon J. Stanworth

Robert Wood Johnson Medical School (RWJMS), Medicine, Division of General Internal Medicine

Research output: Contribution to journal › Comment/debate › peer-review

3 Scopus citations

Abstract

One might not have anticipated that lower hematocrit level is associated with bleeding in patients with hypoproliferative thrombocytopenia as suggested in a secondary analysis by Uhl et al in this issue of Blood.¹ However, patients with hematocrit ≤25% were reported to have a fivefold higher risk of grade ≥3 bleeding (odds ratio [OR], 5.09; 95% confidence interval [CI], 2.65-9.79) and a 1.2-fold higher risk of grade ≥2 bleeding (OR, 1.20; 95% CI, 1.03-1.39) compared with patients with hematocrit ≥29%.

Original language	English (US)
Pages (from-to)	1178-1179
Number of pages	2
Journal	Blood
Volume	130
Issue number	10
DOIs	https://doi.org/10.1182/blood-2017-07-795922
State	Published - Sep 7 2017

All Science Journal Classification (ASJC) codes

Biochemistry
Immunology
Hematology
Cell Biology

Access to Document

10.1182/blood-2017-07-795922

Cite this

@article{f07d93aeb1df479cb32c2713805b6f1b,

title = "Anemia and bleeding in thrombocytopenic patients",

abstract = "One might not have anticipated that lower hematocrit level is associated with bleeding in patients with hypoproliferative thrombocytopenia as suggested in a secondary analysis by Uhl et al in this issue of Blood.1 However, patients with hematocrit ≤25% were reported to have a fivefold higher risk of grade ≥3 bleeding (odds ratio [OR], 5.09; 95% confidence interval [CI], 2.65-9.79) and a 1.2-fold higher risk of grade ≥2 bleeding (OR, 1.20; 95% CI, 1.03-1.39) compared with patients with hematocrit ≥29%.",

author = "Carson, {Jeffrey L.} and Stanworth, {Simon J.}",

note = "Publisher Copyright: {\textcopyright} 2017 by The American Society of Hematology.",

year = "2017",

month = sep,

day = "7",

doi = "10.1182/blood-2017-07-795922",

language = "English (US)",

volume = "130",

pages = "1178--1179",

journal = "Blood",

issn = "0006-4971",

publisher = "American Society of Hematology",

number = "10",

}

TY - JOUR

T1 - Anemia and bleeding in thrombocytopenic patients

AU - Carson, Jeffrey L.

AU - Stanworth, Simon J.

PY - 2017/9/7

Y1 - 2017/9/7

N2 - One might not have anticipated that lower hematocrit level is associated with bleeding in patients with hypoproliferative thrombocytopenia as suggested in a secondary analysis by Uhl et al in this issue of Blood.1 However, patients with hematocrit ≤25% were reported to have a fivefold higher risk of grade ≥3 bleeding (odds ratio [OR], 5.09; 95% confidence interval [CI], 2.65-9.79) and a 1.2-fold higher risk of grade ≥2 bleeding (OR, 1.20; 95% CI, 1.03-1.39) compared with patients with hematocrit ≥29%.

AB - One might not have anticipated that lower hematocrit level is associated with bleeding in patients with hypoproliferative thrombocytopenia as suggested in a secondary analysis by Uhl et al in this issue of Blood.1 However, patients with hematocrit ≤25% were reported to have a fivefold higher risk of grade ≥3 bleeding (odds ratio [OR], 5.09; 95% confidence interval [CI], 2.65-9.79) and a 1.2-fold higher risk of grade ≥2 bleeding (OR, 1.20; 95% CI, 1.03-1.39) compared with patients with hematocrit ≥29%.

UR - http://www.scopus.com/inward/record.url?scp=85029209469&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85029209469&partnerID=8YFLogxK

U2 - 10.1182/blood-2017-07-795922

DO - 10.1182/blood-2017-07-795922

M3 - Comment/debate

C2 - 28882834

AN - SCOPUS:85029209469

SN - 0006-4971

VL - 130

SP - 1178

EP - 1179

JO - Blood

JF - Blood

IS - 10

ER -

Anemia and bleeding in thrombocytopenic patients

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this