Angiotensin-converting enzyme gene polymorphism in systemic hypertension

Ziad A. Abbud; Alan C. Wilson; Nora M. Cosgrove; John B. Kostis

doi:10.1016/S0002-9149(97)00876-X

Angiotensin-converting enzyme gene polymorphism in systemic hypertension

Ziad A. Abbud, Alan C. Wilson, Nora M. Cosgrove, John B. Kostis

Robert Wood Johnson Medical School (RWJMS), Medicine

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

We determined the angiotensin-converting enzyme (ACE) insertion/deletion genotype in 209 hypertensive individuals and in 100 matched normotensive controls. A significant association was detected between hypertension and the deletion/deletion (D/D) genotype of the ACE gene when the relation was adjusted for age, sex, and body mass index.

Original language	English (US)
Pages (from-to)	244-246
Number of pages	3
Journal	American Journal of Cardiology
Volume	81
Issue number	2
DOIs	https://doi.org/10.1016/S0002-9149(97)00876-X
State	Published - Jan 15 1998

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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10.1016/S0002-9149(97)00876-X

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title = "Angiotensin-converting enzyme gene polymorphism in systemic hypertension",

abstract = "We determined the angiotensin-converting enzyme (ACE) insertion/deletion genotype in 209 hypertensive individuals and in 100 matched normotensive controls. A significant association was detected between hypertension and the deletion/deletion (D/D) genotype of the ACE gene when the relation was adjusted for age, sex, and body mass index.",

author = "Abbud, {Ziad A.} and Wilson, {Alan C.} and Cosgrove, {Nora M.} and Kostis, {John B.}",

note = "Funding Information: This study was supported by a grant from the National Institute on Aging, and the National Heart, Lung, and Blood Institute, Bethesda, Maryland. ",

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AU - Wilson, Alan C.

AU - Cosgrove, Nora M.

AU - Kostis, John B.

N1 - Funding Information: This study was supported by a grant from the National Institute on Aging, and the National Heart, Lung, and Blood Institute, Bethesda, Maryland.

PY - 1998/1/15

Y1 - 1998/1/15

N2 - We determined the angiotensin-converting enzyme (ACE) insertion/deletion genotype in 209 hypertensive individuals and in 100 matched normotensive controls. A significant association was detected between hypertension and the deletion/deletion (D/D) genotype of the ACE gene when the relation was adjusted for age, sex, and body mass index.

AB - We determined the angiotensin-converting enzyme (ACE) insertion/deletion genotype in 209 hypertensive individuals and in 100 matched normotensive controls. A significant association was detected between hypertension and the deletion/deletion (D/D) genotype of the ACE gene when the relation was adjusted for age, sex, and body mass index.

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Angiotensin-converting enzyme gene polymorphism in systemic hypertension

Abstract

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