Anti-diabetic Agents from Artemisia Plants

Ilya Raskin (Inventor), David Ribnicky (Inventor)

Research output: Innovation

Abstract


Invention Summary:

Rutgers scientists have discovered that extracts of Artemisia plants, in particular Artemisia dracunculus, could be useful for treating Type 2 diabetes. These extracts can be rapidly and inexpensively obtained in a concentrated form (e.g., powder) by extraction using common mildly polar solvents (e.g., ethanol).

Numerous recent publications from the Rutgers team and colleagues at Pennington Biomedical Research Center (Lousiana State University) demonstrated that Russian tarragon (A. dracunculus) extracts modulate blood glucose levels and enzyme/receptor activities involved in carbohydrate metabolism. The use of A. dracunculus extracts as potential anti-diabetic agent was evaluated in multiple in vitro, in vivo and clinical studies. Experimental results suggest that the mode of action of the extracts is to increase in insulin sensitivity in muscle cells rather than is production in the pancreas.

Market Applications:

  • Type 2 Diabetes
  • Dietary Supplements
  • Functional and Medical Foods
  • Cosmetics

Advantages :

  • A. dracunculus plants can be easily grown with a minimum of time, labor, and cost
  • Extracts can be obtained using a rapid and inexpensive extraction method
  • Natural and inexpensive substance without unwanted side effects
  • Efficacy and mode of action similar to other hypoglycemic drugs
  • No known toxicity
  • Could be used in food, supplements as well as in prescription and non-prescription products

Intellectual Property & Development Status:

  • U.S. Patent 6,893,627 and related foreign patents in several countries.
  • Dr. Raskin has related technologies that are licensed to Nutrasorb. Please contact us for more information.
Original languageEnglish (US)
StatePublished - Aug 2018

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Artemisia
Dietary Supplements
Type 2 Diabetes Mellitus
Araceae
Intellectual Property
Functional Food
Patents
Plant Extracts
Carbohydrate Metabolism
Hypoglycemic Agents
Cosmetics
Powders
Muscle Cells
Prescriptions
Insulin Resistance
Blood Glucose
Biomedical Research
Pancreas
Ethanol
Technology

Keywords

  • Cosmetics
  • Diabetes

Cite this

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title = "Anti-diabetic Agents from Artemisia Plants",
abstract = "Invention Summary: Rutgers scientists have discovered that extracts of Artemisia plants, in particular Artemisia dracunculus, could be useful for treating Type 2 diabetes. These extracts can be rapidly and inexpensively obtained in a concentrated form (e.g., powder) by extraction using common mildly polar solvents (e.g., ethanol). Numerous recent publications from the Rutgers team and colleagues at Pennington Biomedical Research Center (Lousiana State University) demonstrated that Russian tarragon (A. dracunculus) extracts modulate blood glucose levels and enzyme/receptor activities involved in carbohydrate metabolism. The use of A. dracunculus extracts as potential anti-diabetic agent was evaluated in multiple in vitro, in vivo and clinical studies. Experimental results suggest that the mode of action of the extracts is to increase in insulin sensitivity in muscle cells rather than is production in the pancreas. Market Applications: Type 2 Diabetes Dietary Supplements Functional and Medical Foods Cosmetics Advantages : A. dracunculus plants can be easily grown with a minimum of time, labor, and cost Extracts can be obtained using a rapid and inexpensive extraction method Natural and inexpensive substance without unwanted side effects Efficacy and mode of action similar to other hypoglycemic drugs No known toxicity Could be used in food, supplements as well as in prescription and non-prescription products Intellectual Property & Development Status: U.S. Patent 6,893,627 and related foreign patents in several countries. Dr. Raskin has related technologies that are licensed to Nutrasorb. Please contact us for more information.",
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author = "Ilya Raskin and David Ribnicky",
year = "2018",
month = "8",
language = "English (US)",
type = "Patent",

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TY - PAT

T1 - Anti-diabetic Agents from Artemisia Plants

AU - Raskin, Ilya

AU - Ribnicky, David

PY - 2018/8

Y1 - 2018/8

N2 - Invention Summary: Rutgers scientists have discovered that extracts of Artemisia plants, in particular Artemisia dracunculus, could be useful for treating Type 2 diabetes. These extracts can be rapidly and inexpensively obtained in a concentrated form (e.g., powder) by extraction using common mildly polar solvents (e.g., ethanol). Numerous recent publications from the Rutgers team and colleagues at Pennington Biomedical Research Center (Lousiana State University) demonstrated that Russian tarragon (A. dracunculus) extracts modulate blood glucose levels and enzyme/receptor activities involved in carbohydrate metabolism. The use of A. dracunculus extracts as potential anti-diabetic agent was evaluated in multiple in vitro, in vivo and clinical studies. Experimental results suggest that the mode of action of the extracts is to increase in insulin sensitivity in muscle cells rather than is production in the pancreas. Market Applications: Type 2 Diabetes Dietary Supplements Functional and Medical Foods Cosmetics Advantages : A. dracunculus plants can be easily grown with a minimum of time, labor, and cost Extracts can be obtained using a rapid and inexpensive extraction method Natural and inexpensive substance without unwanted side effects Efficacy and mode of action similar to other hypoglycemic drugs No known toxicity Could be used in food, supplements as well as in prescription and non-prescription products Intellectual Property & Development Status: U.S. Patent 6,893,627 and related foreign patents in several countries. Dr. Raskin has related technologies that are licensed to Nutrasorb. Please contact us for more information.

AB - Invention Summary: Rutgers scientists have discovered that extracts of Artemisia plants, in particular Artemisia dracunculus, could be useful for treating Type 2 diabetes. These extracts can be rapidly and inexpensively obtained in a concentrated form (e.g., powder) by extraction using common mildly polar solvents (e.g., ethanol). Numerous recent publications from the Rutgers team and colleagues at Pennington Biomedical Research Center (Lousiana State University) demonstrated that Russian tarragon (A. dracunculus) extracts modulate blood glucose levels and enzyme/receptor activities involved in carbohydrate metabolism. The use of A. dracunculus extracts as potential anti-diabetic agent was evaluated in multiple in vitro, in vivo and clinical studies. Experimental results suggest that the mode of action of the extracts is to increase in insulin sensitivity in muscle cells rather than is production in the pancreas. Market Applications: Type 2 Diabetes Dietary Supplements Functional and Medical Foods Cosmetics Advantages : A. dracunculus plants can be easily grown with a minimum of time, labor, and cost Extracts can be obtained using a rapid and inexpensive extraction method Natural and inexpensive substance without unwanted side effects Efficacy and mode of action similar to other hypoglycemic drugs No known toxicity Could be used in food, supplements as well as in prescription and non-prescription products Intellectual Property & Development Status: U.S. Patent 6,893,627 and related foreign patents in several countries. Dr. Raskin has related technologies that are licensed to Nutrasorb. Please contact us for more information.

KW - Cosmetics

KW - Diabetes

UR - http://rutgers.technologypublisher.com/tech/Anti-diabetic_Agents_from_Artemisia_Plants

M3 - Innovation

ER -