Abstract
Objective: Little is known about whether interventions implemented by specialized Medicaid managed care organizations (MMCOs) contributed to recent stabilization of antipsychotic prescribing to youths in foster care. This study examined a multimodal antipsychotic intervention implemented by a specialized MMCO for youths in foster care with routine mental health screening, health passports, elective psychiatric consultation line, and retrospective drug utilization reviews to determine whether this multimodal intervention significantly reduced antipsychotic dispensing for youths with conditions without US Food and Drug Administration (FDA)–approved indications. Method: Employing a difference-in-differences design, intervention effectiveness for youths in foster care (age 6–17 years) compared with adopted youthss was examined. Analyses were stratified by FDA-indicated conditions, other externalizing conditions, and other internalizing conditions. Outcomes included predicted annual probabilities of any antipsychotic dispensed, antipsychotic dispensed for ≥90 consecutive days, and glucose and lipid testing. Results: Intervention-enrolled youths with FDA-indicated conditions, relative to comparison youths, experienced a 0.6% reduction in any antipsychotic dispensed and 3.1% increase for ≥90 consecutive days dispensed in the 2 years following implementation, both nonsignificant differences. Youths with other externalizing disorders experienced significant reductions, relative to comparison youths, in any antipsychotic dispensed (−6.3%, p < .001) and in ≥90 consecutive days dispensed (−5.5%, p < .001). Youths with other internalizing disorders experienced a significant reduction, relative to comparison youths, in any antipsychotic dispensed (−7.6%, p < .001) and in ≥90 consecutive days dispensed (−5.1%, p < .001). Glucose and lipid testing increased at statistically comparable rates for both groups. Conclusion: MMCO implementation significantly reduced antipsychotic medications without FDA-indicated conditions prescribed to youths, while not significantly affecting antipsychotic medications prescribed to youths with FDA-indicated conditions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 166-176.e3 |
| Journal | Journal of the American Academy of Child and Adolescent Psychiatry |
| Volume | 59 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2020 |
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All Science Journal Classification (ASJC) codes
- Developmental and Educational Psychology
- Psychiatry and Mental health
Keywords
- Medicaid
- antipsychotic agent
- drug utilization review
- managed care organization
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Antipsychotic Use Among Youth in Foster Care Enrolled in a Specialized Managed Care Organization Intervention. / Mackie, Thomas I.; Cook, Sharon; Crystal, Stephen; Olfson, Mark; Akincigil, Ayse.
In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 59, No. 1, 01.2020, p. 166-176.e3.Research output: Contribution to journal › Article
TY - JOUR
T1 - Antipsychotic Use Among Youth in Foster Care Enrolled in a Specialized Managed Care Organization Intervention
AU - Mackie, Thomas I.
AU - Cook, Sharon
AU - Crystal, Stephen
AU - Olfson, Mark
AU - Akincigil, Ayse
PY - 2020/1
Y1 - 2020/1
N2 - Objective: Little is known about whether interventions implemented by specialized Medicaid managed care organizations (MMCOs) contributed to recent stabilization of antipsychotic prescribing to youths in foster care. This study examined a multimodal antipsychotic intervention implemented by a specialized MMCO for youths in foster care with routine mental health screening, health passports, elective psychiatric consultation line, and retrospective drug utilization reviews to determine whether this multimodal intervention significantly reduced antipsychotic dispensing for youths with conditions without US Food and Drug Administration (FDA)–approved indications. Method: Employing a difference-in-differences design, intervention effectiveness for youths in foster care (age 6–17 years) compared with adopted youthss was examined. Analyses were stratified by FDA-indicated conditions, other externalizing conditions, and other internalizing conditions. Outcomes included predicted annual probabilities of any antipsychotic dispensed, antipsychotic dispensed for ≥90 consecutive days, and glucose and lipid testing. Results: Intervention-enrolled youths with FDA-indicated conditions, relative to comparison youths, experienced a 0.6% reduction in any antipsychotic dispensed and 3.1% increase for ≥90 consecutive days dispensed in the 2 years following implementation, both nonsignificant differences. Youths with other externalizing disorders experienced significant reductions, relative to comparison youths, in any antipsychotic dispensed (−6.3%, p < .001) and in ≥90 consecutive days dispensed (−5.5%, p < .001). Youths with other internalizing disorders experienced a significant reduction, relative to comparison youths, in any antipsychotic dispensed (−7.6%, p < .001) and in ≥90 consecutive days dispensed (−5.1%, p < .001). Glucose and lipid testing increased at statistically comparable rates for both groups. Conclusion: MMCO implementation significantly reduced antipsychotic medications without FDA-indicated conditions prescribed to youths, while not significantly affecting antipsychotic medications prescribed to youths with FDA-indicated conditions.
AB - Objective: Little is known about whether interventions implemented by specialized Medicaid managed care organizations (MMCOs) contributed to recent stabilization of antipsychotic prescribing to youths in foster care. This study examined a multimodal antipsychotic intervention implemented by a specialized MMCO for youths in foster care with routine mental health screening, health passports, elective psychiatric consultation line, and retrospective drug utilization reviews to determine whether this multimodal intervention significantly reduced antipsychotic dispensing for youths with conditions without US Food and Drug Administration (FDA)–approved indications. Method: Employing a difference-in-differences design, intervention effectiveness for youths in foster care (age 6–17 years) compared with adopted youthss was examined. Analyses were stratified by FDA-indicated conditions, other externalizing conditions, and other internalizing conditions. Outcomes included predicted annual probabilities of any antipsychotic dispensed, antipsychotic dispensed for ≥90 consecutive days, and glucose and lipid testing. Results: Intervention-enrolled youths with FDA-indicated conditions, relative to comparison youths, experienced a 0.6% reduction in any antipsychotic dispensed and 3.1% increase for ≥90 consecutive days dispensed in the 2 years following implementation, both nonsignificant differences. Youths with other externalizing disorders experienced significant reductions, relative to comparison youths, in any antipsychotic dispensed (−6.3%, p < .001) and in ≥90 consecutive days dispensed (−5.5%, p < .001). Youths with other internalizing disorders experienced a significant reduction, relative to comparison youths, in any antipsychotic dispensed (−7.6%, p < .001) and in ≥90 consecutive days dispensed (−5.1%, p < .001). Glucose and lipid testing increased at statistically comparable rates for both groups. Conclusion: MMCO implementation significantly reduced antipsychotic medications without FDA-indicated conditions prescribed to youths, while not significantly affecting antipsychotic medications prescribed to youths with FDA-indicated conditions.
KW - Medicaid
KW - antipsychotic agent
KW - drug utilization review
KW - managed care organization
UR - http://www.scopus.com/inward/record.url?scp=85076227734&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85076227734&partnerID=8YFLogxK
U2 - 10.1016/j.jaac.2019.04.022
DO - 10.1016/j.jaac.2019.04.022
M3 - Article
C2 - 31071384
AN - SCOPUS:85076227734
VL - 59
SP - 166-176.e3
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
SN - 0890-8567
IS - 1
ER -