APAlyzer: A bioinformatics package for analysis of alternative polyadenylation isoforms

Ruijia Wang, Bin Tian

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Most eukaryotic genes produce alternative polyadenylation (APA) isoforms. APA is dynamically regulated under different growth and differentiation conditions. Here, we present a bioinformatics package, named APAlyzer, for examining 3′UTR APA, intronic APA and gene expression changes using RNA-seq data and annotated polyadenylation sites in the PolyA_DB database. Using APAlyzer and data from the GTEx database, we present APA profiles across human tissues.

Original languageEnglish (US)
Pages (from-to)3907-3909
Number of pages3
JournalBioinformatics
Volume36
Issue number12
DOIs
StatePublished - Mar 31 2020

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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