Apoptosis and signal transduction: clues to a molecular mechanism

Sooja Lee, Sylvia Christakos, Michael B. Small

Research output: Contribution to journalArticlepeer-review

109 Scopus citations

Abstract

Apoptosis, or programmed cell death, plays an essential role in specific cell deletion during normal embryonic and adult development in vertebrate and invertebrate species. Recent evidence suggests that signal transduction pathways governing cellular proliferation and cell cycle progression also mediate the physiological response to changes in the extracellular environment that trigger the anti-proliferatioe state characteristic of apoptosis.

Original languageEnglish (US)
Pages (from-to)286-291
Number of pages6
JournalCurrent Opinion in Cell Biology
Volume5
Issue number2
DOIs
StatePublished - Apr 1993

All Science Journal Classification (ASJC) codes

  • Cell Biology

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