Apple II software for M13 shotgun DNA sequencing

Roger Larson, Joachim Messing

Research output: Contribution to journalArticlepeer-review

80 Scopus citations


A set of programs is presented for the reconstruction of a DNA sequence from data generated by the M13 shotgun sequencing technique. Once the sequence has been established and stored other programs are used for its analysis. The programs have been written for the Apple II microcmputer. A minimun investment is required for the hardware and the software is easily interchangable between the growing number of interested researchers. Copies are available in ready to use form.

Original languageEnglish (US)
Pages (from-to)39-49
Number of pages11
JournalNucleic acids research
Issue number1
StatePublished - Jan 11 1982
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics

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