Application of metabonomics in complicated theory system research of traditional Chinese medicine

Wei Jia, Ping Liu, Jian Jiang, Min Jun Chen, Li Ping Zhao, Ming Mei Zhou, Li Ping Yang, Mi Qu Wang, Ming Feng Qiu, Yong Yu Zhang

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Metabonomics, a new and rapid-developing technology, will be powerful means to the research of complexed theory system and modernization of traditional Chinese medicine (TCM). Discovery of biomarkers and analysis of common properties from the metabolome of a specific TCM syndrome will facilitate the modernized study of TCM system, promote the quantitative and scientific elucidation of TCM syndrome differentiation, provide an in-depth understanding of the TCM theory of Zang-xiang, help predict the disease on-set, and achieve a comprehensive evaluation of systemic clinical efficacy, safety and mechanism of action of the TCM combination formulas along with a better understanding of intestinal microflora ecology. The new approach with combined metabonomics and TCM methodologies will provide a new pathway and methodology for the study of complicated theory system of TCM and its modernization.

Original languageEnglish (US)
Pages (from-to)621-624
Number of pages4
JournalZhongguo Zhongyao Zazhi
Volume31
Issue number8
StatePublished - 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Complementary and alternative medicine
  • Pharmacology (medical)

Keywords

  • Complexed theory system of TCM
  • Intestinal microflora ecology
  • Metabonomics
  • Treatment based on syndrome differentiation
  • Zang-xiang theory

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