Application of Toxicogenomics in Predicting Hepatotoxicity - Potentials and Challenges

Wen Lin, Guoxiang Shen, Tin Oo Khor, Ah-Ng Kong

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationHepatotoxicity
Subtitle of host publicationFrom Genomics to in vitro and in vivo Models
PublisherJohn Wiley & Sons, Ltd
Pages447-463
Number of pages17
ISBN (Print)9780470057162
DOIs
StatePublished - Feb 27 2008

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Toxicogenetics
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All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Keywords

  • Acute and chronic liver diseases
  • Drug withdrawal post-marketing
  • Drug-induced hepatotoxicity
  • Drug-induced idiosyncratic hepatotoxicity
  • Gene expression profiles
  • Genome-scale DNA sequences
  • Microarray-based toxicogenomics
  • Potential liver toxicity
  • Primary upstream events
  • Serum toxicity biomarkers level

Cite this

Lin, W., Shen, G., Khor, T. O., & Kong, A-N. (2008). Application of Toxicogenomics in Predicting Hepatotoxicity - Potentials and Challenges. In Hepatotoxicity: From Genomics to in vitro and in vivo Models (pp. 447-463). John Wiley & Sons, Ltd. https://doi.org/10.1002/9780470516751.ch17
Lin, Wen ; Shen, Guoxiang ; Khor, Tin Oo ; Kong, Ah-Ng. / Application of Toxicogenomics in Predicting Hepatotoxicity - Potentials and Challenges. Hepatotoxicity: From Genomics to in vitro and in vivo Models. John Wiley & Sons, Ltd, 2008. pp. 447-463
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Lin, W, Shen, G, Khor, TO & Kong, A-N 2008, Application of Toxicogenomics in Predicting Hepatotoxicity - Potentials and Challenges. in Hepatotoxicity: From Genomics to in vitro and in vivo Models. John Wiley & Sons, Ltd, pp. 447-463. https://doi.org/10.1002/9780470516751.ch17

Application of Toxicogenomics in Predicting Hepatotoxicity - Potentials and Challenges. / Lin, Wen; Shen, Guoxiang; Khor, Tin Oo; Kong, Ah-Ng.

Hepatotoxicity: From Genomics to in vitro and in vivo Models. John Wiley & Sons, Ltd, 2008. p. 447-463.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Lin W, Shen G, Khor TO, Kong A-N. Application of Toxicogenomics in Predicting Hepatotoxicity - Potentials and Challenges. In Hepatotoxicity: From Genomics to in vitro and in vivo Models. John Wiley & Sons, Ltd. 2008. p. 447-463 https://doi.org/10.1002/9780470516751.ch17