Aptatag-based multiplexed assay for protein detection by surface-enhanced Raman spectroscopy

Laura Fabris; Martin Schierhorn; Martin Moskovits; Guillermo C. Bazan

doi:10.1002/smll.201000262

Aptatag-based multiplexed assay for protein detection by surface-enhanced Raman spectroscopy

Laura Fabris, Martin Schierhorn, Martin Moskovits, Guillermo C. Bazan

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Silver-nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity.

Original language	English (US)
Pages (from-to)	1550-1557
Number of pages	8
Journal	Small
Volume	6
Issue number	14
DOIs	https://doi.org/10.1002/smll.201000262
State	Published - Jul 19 2010

All Science Journal Classification (ASJC) codes

Biotechnology
Biomaterials
Chemistry(all)
Materials Science(all)

Keywords

Aptamers
Bioassays
Nanoparticles
Proteins
Raman spectroscopy

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10.1002/smll.201000262

Cite this

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title = "Aptatag-based multiplexed assay for protein detection by surface-enhanced Raman spectroscopy",

abstract = "Silver-nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity.",

keywords = "Aptamers, Bioassays, Nanoparticles, Proteins, Raman spectroscopy",

author = "Laura Fabris and Martin Schierhorn and Martin Moskovits and Bazan, {Guillermo C.}",

year = "2010",

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doi = "10.1002/smll.201000262",

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T1 - Aptatag-based multiplexed assay for protein detection by surface-enhanced Raman spectroscopy

AU - Fabris, Laura

AU - Schierhorn, Martin

AU - Moskovits, Martin

AU - Bazan, Guillermo C.

PY - 2010/7/19

Y1 - 2010/7/19

N2 - Silver-nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity.

AB - Silver-nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity.

KW - Aptamers

KW - Bioassays

KW - Nanoparticles

KW - Proteins

KW - Raman spectroscopy

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DO - 10.1002/smll.201000262

M3 - Article

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AN - SCOPUS:77954687757

SN - 1613-6810

VL - 6

SP - 1550

EP - 1557

JO - Small

JF - Small

IS - 14

ER -

Aptatag-based multiplexed assay for protein detection by surface-enhanced Raman spectroscopy

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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