Artificial Insemination by Donors

The Need for Genetic Screening: Late-Infantile GM2-Gangliosidosis Resulting from This Technique

William G. Johnson, Robin C. Schwartz, Abe M. Chutorian, William Johnson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

ARTIFICIAL insemination by donor has become a widely accepted method to induce pregnancy for infertile couples and to decrease the risk of inherited diseases. With increasing use of this method, however, some infants with genetic diseases will be born from such pregnancies. The only recent study1 of practices and policies in donor insemination concluded that donors of semen were screened only superficially for genetic diseases, although 26 per cent of physicians practicing donor insemination used the procedure to prevent transmission of a genetic disease. The GM2-gangliosidoses are recessively inherited deficiencies of the enzyme beta-D-Ɲ-acetylhexosaminidase2; in these disorders,. . .

Original languageEnglish (US)
Pages (from-to)755-757
Number of pages3
JournalNew England Journal of Medicine
Volume304
Issue number13
DOIs
StatePublished - Mar 26 1981
Externally publishedYes

Fingerprint

GM2 Gangliosidosis
Genetic Testing
Inborn Genetic Diseases
Insemination
Tissue Donors
4 alpha-glucanotransferase
Pregnancy
Physicians

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{0e322ba01d5c49acb07aa1ccaeb0874e,
title = "Artificial Insemination by Donors: The Need for Genetic Screening: Late-Infantile GM2-Gangliosidosis Resulting from This Technique",
abstract = "ARTIFICIAL insemination by donor has become a widely accepted method to induce pregnancy for infertile couples and to decrease the risk of inherited diseases. With increasing use of this method, however, some infants with genetic diseases will be born from such pregnancies. The only recent study1 of practices and policies in donor insemination concluded that donors of semen were screened only superficially for genetic diseases, although 26 per cent of physicians practicing donor insemination used the procedure to prevent transmission of a genetic disease. The GM2-gangliosidoses are recessively inherited deficiencies of the enzyme beta-D-Ɲ-acetylhexosaminidase2; in these disorders,. . .",
author = "Johnson, {William G.} and Schwartz, {Robin C.} and Chutorian, {Abe M.} and William Johnson",
year = "1981",
month = "3",
day = "26",
doi = "10.1056/NEJM198103263041303",
language = "English (US)",
volume = "304",
pages = "755--757",
journal = "New England Journal of Medicine",
issn = "0028-4793",
publisher = "Massachussetts Medical Society",
number = "13",

}

Artificial Insemination by Donors : The Need for Genetic Screening: Late-Infantile GM2-Gangliosidosis Resulting from This Technique. / Johnson, William G.; Schwartz, Robin C.; Chutorian, Abe M.; Johnson, William.

In: New England Journal of Medicine, Vol. 304, No. 13, 26.03.1981, p. 755-757.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Artificial Insemination by Donors

T2 - The Need for Genetic Screening: Late-Infantile GM2-Gangliosidosis Resulting from This Technique

AU - Johnson, William G.

AU - Schwartz, Robin C.

AU - Chutorian, Abe M.

AU - Johnson, William

PY - 1981/3/26

Y1 - 1981/3/26

N2 - ARTIFICIAL insemination by donor has become a widely accepted method to induce pregnancy for infertile couples and to decrease the risk of inherited diseases. With increasing use of this method, however, some infants with genetic diseases will be born from such pregnancies. The only recent study1 of practices and policies in donor insemination concluded that donors of semen were screened only superficially for genetic diseases, although 26 per cent of physicians practicing donor insemination used the procedure to prevent transmission of a genetic disease. The GM2-gangliosidoses are recessively inherited deficiencies of the enzyme beta-D-Ɲ-acetylhexosaminidase2; in these disorders,. . .

AB - ARTIFICIAL insemination by donor has become a widely accepted method to induce pregnancy for infertile couples and to decrease the risk of inherited diseases. With increasing use of this method, however, some infants with genetic diseases will be born from such pregnancies. The only recent study1 of practices and policies in donor insemination concluded that donors of semen were screened only superficially for genetic diseases, although 26 per cent of physicians practicing donor insemination used the procedure to prevent transmission of a genetic disease. The GM2-gangliosidoses are recessively inherited deficiencies of the enzyme beta-D-Ɲ-acetylhexosaminidase2; in these disorders,. . .

UR - http://www.scopus.com/inward/record.url?scp=0019482917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019482917&partnerID=8YFLogxK

U2 - 10.1056/NEJM198103263041303

DO - 10.1056/NEJM198103263041303

M3 - Article

VL - 304

SP - 755

EP - 757

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 13

ER -