Association of metabolic syndrome with morbidity and mortality in emergency general surgery

Samer Elsamna, Omar Elkattawy, Aziz M. Merchant

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background: Metabolic syndrome (MetS) is defined by numerous comorbidities. We sought to assess MetS's effect on the 7 main emergency general surgery (EGS) procedures that constitute 80% of EGS procedures, mortalities, complications, and costs. Methods: Data were acquired from the ACS-NSQIP database from 2005 to 2017. Current procedural terminology (CPT) codes were utilized to identify cases. Patients with obesity, diabetes, and hypertension were defined as having MetS. MetS and non-MetS cohorts were propensity score matched, compared by outcomes, and assessed with multivariate logistic regression to attain odds ratios (OR). Results: Of 752,023 cases, 41,788 (5.6%) MetS cases were identified. Significant outcomes included superficial infection (OR: 1.51), pulmonary complications (OR: 1.17), renal complications (OR: 1.82), cumulative morbidity (OR: 1.22), and hospital readmission (OR: 1.41). Conclusions: For patients undergoing these procedures, MetS increased risk for comorbidities and hospital readmission. MetS had a significant impact on mortality only for appendectomy.

Original languageEnglish (US)
Pages (from-to)448-453
Number of pages6
JournalAmerican journal of surgery
Issue number2
StatePublished - Aug 2020

All Science Journal Classification (ASJC) codes

  • Surgery


  • Emergency
  • General surgery
  • Metabolic syndrome
  • Outcomes


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