Association of plasma parathyroid hormone with metabolic syndrome and risk for cardiovascular disease

Cindy Huang, Sue Shapses, Xiangbing Wang

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

Objective: To review the current literature investigating the association of plasma parathyroid hormone (PTH) with the prevalence of metabolic syndrome and the risk for cardiovascular disease (CVD).Methods: We conducted a search of PubMed and Medline database using the terms hyperparathyroidism, metabolic syndrome, hypertension, hyperlipidemia, hyperglycemia, and CVD. We reviewed relevant studies from 2004 to 2012.Results: The current literature assessing the association of plasma PTH levels with metabolic syndrome and CVD is inconsistent; however, positive associations among hyperparathyroidism, metabolic syndrome, and CVD were found in a majority of the studies. The differences in the study populations may partly explain the mixed results.Conclusion: In the general population, a high serum PTH level predisposes patients to CVD mortality. Further research is needed to determine the role of PTH in the etiology of metabolic syndrome and CVD.

Original languageEnglish (US)
Pages (from-to)712-717
Number of pages6
JournalEndocrine Practice
Volume19
Issue number4
DOIs
StatePublished - Jul 1 2013

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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