Associations between personal exposures and ambient concentrations of nitrogen dioxide: A quantitative research synthesis

Q. Y. Meng, D. Svendsgaard, D. J. Kotchmar, J. P. Pinto

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Although positive associations between ambient NO 2 concentrations and personal exposures have generally been found by exposure studies, the strength of the associations varied among studies. Differences in results could be related to differences in study design and in exposure factors. However, the effects of study design, exposure factors, and sampling and measurement errors on the strength of the personal-ambient associations have not been evaluated quantitatively in a systematic manner. A quantitative research synthesis was conducted to examine these issues based on peer-reviewed publications in the past 30 years. Factors affecting the strength of the personal-ambient associations across the studies were also examined with meta-regression. Ambient NO 2 was found to be significantly associated with personal NO 2 exposures, with estimates of 0.42, 0.16, and 0.72 for overall pooled, longitudinal and daily average correlation coefficients based on random-effects meta-analysis. This conclusion was robust after correction for publication bias with correlation coefficients of 0.37, 0.16 and 0.45. We found that season and some population characteristics, such as pre-existing disease, were significant factors affecting the strength of the personal-ambient associations. More meaningful and rigorous comparisons would be possible if greater detail were published on the study design (e.g. local and indoor sources, housing characteristics, etc.) and data quality (e.g., detection limits and percent of data above detection limits).

Original languageEnglish (US)
Pages (from-to)322-329
Number of pages8
JournalAtmospheric Environment
Volume57
DOIs
StatePublished - Sep 2012

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)
  • Atmospheric Science

Keywords

  • Exposure factors
  • Meta analysis
  • NO
  • Personal exposure
  • Personal-ambient association

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