Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a child

Larry Frohman, Roger Turbin, Leonard Bielory, Leo Wolansky, W. Clark Lambert, Stuart Cook

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

PURPOSE: To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population. DESIGN: Interventional case report. METHODS: A 4-year-old developed four episodes of bilateral optic neuritis with mild concurrent weakness, ataxia, or dizziness; one episode of unilateral optic neuritis; and one episode of weakness over a period of 4 years. RESULTS: Autoimmune optic neuropathy was diagnosed because of the presence of anticardiolipin antibody and an abnormal skin biopsy with thrombin and immunoreactant deposition. She was treated with corticosteroids, aspirin, and gammaglobulin. This diminished the frequency and intensity of her attacks. CONCLUSION: This case represents the diagnosis and treatment of AON in a child.

Original languageEnglish (US)
Pages (from-to)358-360
Number of pages3
JournalAmerican journal of ophthalmology
Volume136
Issue number2
DOIs
StatePublished - Aug 1 2003

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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