Automated analysis of protein NMR assignments and structures

Michael C. Baran, Yuanpeng J. Huang, Hunter N.B. Moseley, Gaetano T. Montelione

Research output: Contribution to journalArticlepeer-review

75 Scopus citations

Abstract

Recent developments provide automated analysis of NMR assignments and 3D structures. These approaches are generally applicable to proteins ranging from about 50 to 150 amino acids. To date, little work has focused on the specific problems associated with nucleic acid structures. As a result, there has been no community-wide consensus reached on how to evaluate the accuracy and precision of a protein NMR structure. Nevertheless, when good quality data are available automated analysis of protein NMR assignment and structures can be both fast and reliable.

Original languageEnglish (US)
Pages (from-to)3541-3555
Number of pages15
JournalChemical Reviews
Volume104
Issue number8
DOIs
StatePublished - Aug 2004

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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