Automatic liver segmentation and hepatic fat fraction assessment in MRI

Zhennan Yan, Chaowei Tan, Shaoting Zhang, Yan Zhou, Boubakeur Belaroussi, Hui Jing Yu, Colin Miller, Dimitris N. Metaxas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations


Automated assessment of hepatic fat fraction is clinically important. A robust and precise segmentation would enable accurate, objective and consistent measurement of liver fat fraction for disease quantification, therapy monitoring and drug development. However, segmenting the liver in clinical trials is a challenging task due to the variability of liver anatomy as well as the diverse sources the images were acquired from. In this paper, we propose an automated and robust framework for liver segmentation and assessment. It uses single statistical atlas registration to initialize a robust deformable model to get fine segmentation. Fat fraction map is computed by using chemical shift based method in the delineated region of liver. This proposed method is validated on 14 abdominal magnetic resonance (MR) volumetric scans. The qualitative and quantitative comparisons show that our proposed method can achieve better segmentation accuracy with less variance comparing with an automatic graph cut method. Experimental results demonstrate the promises of our assessment framework.

Original languageEnglish (US)
Title of host publicationProceedings - International Conference on Pattern Recognition
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages6
ISBN (Electronic)9781479952083
StatePublished - Dec 4 2014
Event22nd International Conference on Pattern Recognition, ICPR 2014 - Stockholm, Sweden
Duration: Aug 24 2014Aug 28 2014

Publication series

NameProceedings - International Conference on Pattern Recognition
ISSN (Print)1051-4651


Other22nd International Conference on Pattern Recognition, ICPR 2014

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition


  • Deformable model
  • MRI
  • Segmentation

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