Autoregulated pulsed-DC mode iontophoretic transdermal system

C. Carley, S. Wolpert, John Li

Research output: Contribution to conferencePaper

Abstract

An autoregulated pulsed-DC iontophoretic device with slow turn-on current has been developed. A specialized high-frequency pulse with a duty cycle of 50% or less is used which will reduce skin irritation due to polarization effects. To avoid patient discomfort, current delivery is increased gradually over a two-minute period to allow the skin to adapt to the applied current level. The rate of drug delivery is regulated by controlling the energy of the delivered pulse. For antihypertensive-drug administration, the device has the arterial pressure and continually readjusts delivery rates to keep it close to a desired target value.

Original languageEnglish (US)
Pages51-52
Number of pages2
Publication statusPublished - Dec 1 1989
EventProceedings of the Fifteenth Annual Northeast Bioengineering Conference - Boston, MA, USA
Duration: Mar 27 1989Mar 28 1989

Other

OtherProceedings of the Fifteenth Annual Northeast Bioengineering Conference
CityBoston, MA, USA
Period3/27/893/28/89

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All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

Carley, C., Wolpert, S., & Li, J. (1989). Autoregulated pulsed-DC mode iontophoretic transdermal system. 51-52. Paper presented at Proceedings of the Fifteenth Annual Northeast Bioengineering Conference, Boston, MA, USA, .