Axonal transport of gangliosides in the goldfish optic nerve

David S. Forman, Robert W. Ledeen

Research output: Contribution to journalArticlepeer-review

73 Scopus citations

Abstract

Radioactive glucosamine and N-acetylmannosamine injected into the goldfish eye are incorporated into gangliosides that undergo rapid axonal transport to the optic nerve terminals. All ganglioside fractions are labeled. These data provide the first evidence that axonal transport has a role in neuronal ganglioside function and metabolism.

Original languageEnglish (US)
Pages (from-to)630-633
Number of pages4
JournalScience
Volume177
Issue number4049
DOIs
StatePublished - 1972
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General

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