B cells masquerade as dendritic cells

Lisa K. Denzin

doi:10.1016/j.it.2022.03.008

B cells masquerade as dendritic cells

Lisa K. Denzin

Robert Wood Johnson Medical School (RWJMS), Child Health Institute of New Jersey (CHINJ)

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

In a recent paper, Schriek et al. show that, in a complement-dependent reaction, marginal zone B cells (MZBs) steal MHC class II (MHCII) from dendritic cells (DCs). Activation of T cells by stolen MHCII complexes potentially allows MZBs to augment or regulate T cell activation in ways that are distinct from DCs.

Original language	English (US)
Pages (from-to)	340-342
Number of pages	3
Journal	Trends in Immunology
Volume	43
Issue number	5
DOIs	https://doi.org/10.1016/j.it.2022.03.008
State	Published - May 2022

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology

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10.1016/j.it.2022.03.008

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title = "B cells masquerade as dendritic cells",

abstract = "In a recent paper, Schriek et al. show that, in a complement-dependent reaction, marginal zone B cells (MZBs) steal MHC class II (MHCII) from dendritic cells (DCs). Activation of T cells by stolen MHCII complexes potentially allows MZBs to augment or regulate T cell activation in ways that are distinct from DCs.",

author = "Denzin, {Lisa K.}",

note = "Funding Information: I thank Derek Sant{\textquoteright}Angelo for helpful discussions. L.K.D is supported by grants from the National Institutes of Health ( R01 AI117535 and P30 CA072720 ), the Robert Wood Johnson Foundation (Grant 67038 to the Child Health Institute of New Jersey), and the Barile Children's Medical Research Trust . Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

year = "2022",

month = may,

doi = "10.1016/j.it.2022.03.008",

language = "English (US)",

volume = "43",

pages = "340--342",

journal = "Trends in Immunology",

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T1 - B cells masquerade as dendritic cells

AU - Denzin, Lisa K.

N1 - Funding Information: I thank Derek Sant’Angelo for helpful discussions. L.K.D is supported by grants from the National Institutes of Health ( R01 AI117535 and P30 CA072720 ), the Robert Wood Johnson Foundation (Grant 67038 to the Child Health Institute of New Jersey), and the Barile Children's Medical Research Trust . Publisher Copyright: © 2022 Elsevier Ltd

PY - 2022/5

Y1 - 2022/5

N2 - In a recent paper, Schriek et al. show that, in a complement-dependent reaction, marginal zone B cells (MZBs) steal MHC class II (MHCII) from dendritic cells (DCs). Activation of T cells by stolen MHCII complexes potentially allows MZBs to augment or regulate T cell activation in ways that are distinct from DCs.

AB - In a recent paper, Schriek et al. show that, in a complement-dependent reaction, marginal zone B cells (MZBs) steal MHC class II (MHCII) from dendritic cells (DCs). Activation of T cells by stolen MHCII complexes potentially allows MZBs to augment or regulate T cell activation in ways that are distinct from DCs.

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DO - 10.1016/j.it.2022.03.008

M3 - Short survey

C2 - 35379581

AN - SCOPUS:85128273888

SN - 1471-4906

VL - 43

SP - 340

EP - 342

JO - Trends in Immunology

JF - Trends in Immunology

IS - 5

ER -

B cells masquerade as dendritic cells

Abstract

All Science Journal Classification (ASJC) codes

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