Balancing Act: Maintaining Amino Acid Levels in the Autistic Brain

Thomas M. Maynard, M. Chiara Manzini

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations

Abstract

The ever-expanding number of genes that are mutated in autism is showing us how imbalances in fundamental cellular processes can lead to disease. A recent study by Tărlungeanu et al. (2016) identifies a form of ASD resulting from a failure of the brain to properly import amino acids.

Original languageEnglish (US)
Pages (from-to)476-479
Number of pages4
JournalNeuron
Volume93
Issue number3
DOIs
StatePublished - Feb 8 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Keywords

  • amino acid transport
  • autism spectrum disorder
  • blood brain barrier
  • brain metabolism
  • branched amino acids
  • mTor
  • protein synthesis

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