Barrett's esophagus: Histology and immunohistology

Hugh Barr, Melissa P. Upton, Roy C. Orlando, David Armstrong, Michael Vieth, Helmut Neumann, Cord Langner, Elizabeth L. Wiley, Kiron M. Das, Octavia E. Pickett-Blakely, Manisha Bajpai, Peter S. Amenta, Ana Bennett, James J. Going, Mamoun Younes, Helen H. Wang, Antonio Taddei, Giancarlo Freschi, Maria Novella Ringressi, Duccio Rossi Degli'InnocentiFrancesca Castiglione, Paolo Bechi

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The following on histology and immunohistology of Barrett's esophagus (BE) includes commentaries on the various difficulties remaining in reaching a consensus on the definition of BE; the difficulties in the characterization of intestinal and cardiac mucosa, and in the role of submucosal glands in the development of BE; the importance of a new monoclonal antibody to recognize esophageal intestinal mucosa; the importance of pseudo goblet cells; the best techniques for the endoscopic detection of Barrett's epithelium; and the biomarkers for identification of patients predisposed to the development of BE.

Original languageEnglish (US)
Pages (from-to)76-92
Number of pages17
JournalAnnals of the New York Academy of Sciences
Issue number1
StatePublished - Sep 2011

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science


  • ACG guidelines
  • Adenocarcinoma
  • BSG guidelines
  • CDX2
  • Cardiac mucosa
  • Cytokeratin 20
  • Cytokeratin 7
  • Das-1
  • Epithelium
  • Esophageal glands
  • Esophageal microanatomy
  • Four-quadrant biopsies
  • Gastroesophageal junction
  • Goblet cells
  • Immunohistochemistry
  • Intestinal metaplasia
  • MUC2
  • Montreal Working Group
  • Oxyntic cells
  • Prague criteria
  • Pseudogoblet cells
  • Reflux esophagitis
  • Submucosal glands
  • Villin


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