Abstract
The following on histology and immunohistology of Barrett's esophagus (BE) includes commentaries on the various difficulties remaining in reaching a consensus on the definition of BE; the difficulties in the characterization of intestinal and cardiac mucosa, and in the role of submucosal glands in the development of BE; the importance of a new monoclonal antibody to recognize esophageal intestinal mucosa; the importance of pseudo goblet cells; the best techniques for the endoscopic detection of Barrett's epithelium; and the biomarkers for identification of patients predisposed to the development of BE.
Original language | English (US) |
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Pages (from-to) | 76-92 |
Number of pages | 17 |
Journal | Annals of the New York Academy of Sciences |
Volume | 1232 |
Issue number | 1 |
DOIs | |
State | Published - Sep 2011 |
All Science Journal Classification (ASJC) codes
- General Neuroscience
- General Biochemistry, Genetics and Molecular Biology
- History and Philosophy of Science
Keywords
- ACG guidelines
- Adenocarcinoma
- BSG guidelines
- CDX2
- Cardiac mucosa
- Cytokeratin 20
- Cytokeratin 7
- Das-1
- Epithelium
- Esophageal glands
- Esophageal microanatomy
- Four-quadrant biopsies
- Gastroesophageal junction
- Goblet cells
- Immunohistochemistry
- Intestinal metaplasia
- MUC2
- Montreal Working Group
- Oxyntic cells
- Prague criteria
- Pseudogoblet cells
- Reflux esophagitis
- Submucosal glands
- Villin