Forty-six percent of added [14C] versicolorin A was efficiently converted to aflatoxin B1 by a resting cell culture of wild-type Aspergillus parasiticus. The labeled pigment was isolated from [1-14C]acetate enriched cultures of a mutant of A. parasiticus that elaborates several versicolorin pigments, but no aflatoxins. The high level of incorporation into aflatoxin B1 and the relative specific activity of 0.475 of aflatoxin isolated from the culture of A. parasiticus enriched with [14C]versicolorin A indicate that this C-18 polyketide-derived hydroxyanthraquinone is a precursor to aflatoxin B1.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of agricultural and food chemistry|
|State||Published - Nov 1 1976|
All Science Journal Classification (ASJC) codes
- Agricultural and Biological Sciences(all)