Blood Lead Levels of Children in Flint, Michigan: 2006-2016

Hernán F. Gómez, Dominic A. Borgialli, Mahesh Sharman, Keneil K. Shah, Anthony J. Scolpino, James M. Oleske, John D. Bogden

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective: We evaluated the increases in blood lead levels (BLLs) observed in young children in Flint, Michigan, during their exposure to corrosive Flint River water during the years 2014 and 2015 and compared their BLLs to those of Flint children measured during the years 2006-2013 and 2016. Study design: This was a retrospective study design using BLLs extracted from databases from 2006 to 2016. We analyzed a population sample of 15 817 BLLs from children aged ≤5 years with potential exposure to contaminated Flint River water. Percentages of BLLs ≥5.0 µg/dL and geometric mean (GM) BLLs were analyzed over time. Results: A significant decline in the percentages of BLLs ≥5.0 µg/dL from 11.8% in 2006 to 3.2% in 2016 was observed (P <.001). GM ± SE BLLs decreased from 2.33 ± 0.04 µg/dL in 2006 to 1.15 ± 0.02 µg/dL in 2016 (P <.001). GM BLLs increased twice: from 1.75 ± 0.03 µg/dL to 1.87 ± 0.03 µg/dL (2010-2011) and from 1.19 ± 0.02 µg/dL to 1.30 ± 0.02 µg/dL (2014-2015). Overall, from 2006 to 2016, there was a 72.9% decrease in the percentage of children with BLLs ≥5.0 µg/dL and a 50.6% decrease in GM BLLs. Conclusion: These findings suggest that the 11 year trend of annual decreases in BLLs in children in Flint, Michigan, reversed to a degree consistent with random variation from 2010 to 2011, and again during the exposure to Flint River water in 2014-2015. Historically, public health efforts to reduce BLLs of young children in Flint have been effective over the 11-year period studied.

Original languageEnglish (US)
Pages (from-to)158-164
Number of pages7
JournalJournal of Pediatrics
Volume197
DOIs
StatePublished - Jun 2018

Fingerprint

Rivers
Lead
Water
Caustics
Retrospective Studies
Public Health
Databases
Population

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Keywords

  • CDC
  • Centers for Disease Control and Prevention
  • Flint, Michigan
  • blood lead levels
  • children
  • lead
  • toxicology

Cite this

Gómez, Hernán F. ; Borgialli, Dominic A. ; Sharman, Mahesh ; Shah, Keneil K. ; Scolpino, Anthony J. ; Oleske, James M. ; Bogden, John D. / Blood Lead Levels of Children in Flint, Michigan : 2006-2016. In: Journal of Pediatrics. 2018 ; Vol. 197. pp. 158-164.
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abstract = "Objective: We evaluated the increases in blood lead levels (BLLs) observed in young children in Flint, Michigan, during their exposure to corrosive Flint River water during the years 2014 and 2015 and compared their BLLs to those of Flint children measured during the years 2006-2013 and 2016. Study design: This was a retrospective study design using BLLs extracted from databases from 2006 to 2016. We analyzed a population sample of 15 817 BLLs from children aged ≤5 years with potential exposure to contaminated Flint River water. Percentages of BLLs ≥5.0 µg/dL and geometric mean (GM) BLLs were analyzed over time. Results: A significant decline in the percentages of BLLs ≥5.0 µg/dL from 11.8{\%} in 2006 to 3.2{\%} in 2016 was observed (P <.001). GM ± SE BLLs decreased from 2.33 ± 0.04 µg/dL in 2006 to 1.15 ± 0.02 µg/dL in 2016 (P <.001). GM BLLs increased twice: from 1.75 ± 0.03 µg/dL to 1.87 ± 0.03 µg/dL (2010-2011) and from 1.19 ± 0.02 µg/dL to 1.30 ± 0.02 µg/dL (2014-2015). Overall, from 2006 to 2016, there was a 72.9{\%} decrease in the percentage of children with BLLs ≥5.0 µg/dL and a 50.6{\%} decrease in GM BLLs. Conclusion: These findings suggest that the 11 year trend of annual decreases in BLLs in children in Flint, Michigan, reversed to a degree consistent with random variation from 2010 to 2011, and again during the exposure to Flint River water in 2014-2015. Historically, public health efforts to reduce BLLs of young children in Flint have been effective over the 11-year period studied.",
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Blood Lead Levels of Children in Flint, Michigan : 2006-2016. / Gómez, Hernán F.; Borgialli, Dominic A.; Sharman, Mahesh; Shah, Keneil K.; Scolpino, Anthony J.; Oleske, James M.; Bogden, John D.

In: Journal of Pediatrics, Vol. 197, 06.2018, p. 158-164.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Blood Lead Levels of Children in Flint, Michigan

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AU - Gómez, Hernán F.

AU - Borgialli, Dominic A.

AU - Sharman, Mahesh

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AB - Objective: We evaluated the increases in blood lead levels (BLLs) observed in young children in Flint, Michigan, during their exposure to corrosive Flint River water during the years 2014 and 2015 and compared their BLLs to those of Flint children measured during the years 2006-2013 and 2016. Study design: This was a retrospective study design using BLLs extracted from databases from 2006 to 2016. We analyzed a population sample of 15 817 BLLs from children aged ≤5 years with potential exposure to contaminated Flint River water. Percentages of BLLs ≥5.0 µg/dL and geometric mean (GM) BLLs were analyzed over time. Results: A significant decline in the percentages of BLLs ≥5.0 µg/dL from 11.8% in 2006 to 3.2% in 2016 was observed (P <.001). GM ± SE BLLs decreased from 2.33 ± 0.04 µg/dL in 2006 to 1.15 ± 0.02 µg/dL in 2016 (P <.001). GM BLLs increased twice: from 1.75 ± 0.03 µg/dL to 1.87 ± 0.03 µg/dL (2010-2011) and from 1.19 ± 0.02 µg/dL to 1.30 ± 0.02 µg/dL (2014-2015). Overall, from 2006 to 2016, there was a 72.9% decrease in the percentage of children with BLLs ≥5.0 µg/dL and a 50.6% decrease in GM BLLs. Conclusion: These findings suggest that the 11 year trend of annual decreases in BLLs in children in Flint, Michigan, reversed to a degree consistent with random variation from 2010 to 2011, and again during the exposure to Flint River water in 2014-2015. Historically, public health efforts to reduce BLLs of young children in Flint have been effective over the 11-year period studied.

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Gómez HF, Borgialli DA, Sharman M, Shah KK, Scolpino AJ, Oleske JM et al. Blood Lead Levels of Children in Flint, Michigan: 2006-2016. Journal of Pediatrics. 2018 Jun;197:158-164. https://doi.org/10.1016/j.jpeds.2017.12.063