Borderline Brenner tumor: A review of the literature

Ruifang Zheng, Debra S. Heller

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

Brenner tumors arise from ovarian epithelium, accounting for approximately 5% of benign ovarian epithelial tumors. The World Health Organization classification groups them into benign, borderline, and malignant on the basis of proliferation and invasiveness, and borderline Brenner tumor is defined as ''displaying epithelial proliferation beyond that seen in benign Brenner's tumor, but lacking stromal invasion.'' Borderline Brenner tumors are rare. Fewer than 60 cases have been reported. The more recent articles mostly focus on pathogenesis. We reviewed the literature on borderline Brenner tumor and have summarized the clinical and pathologic findings, as well as the treatment, differential diagnoses, and recent advances in histogenesis and molecular pathogenesis.

Original languageEnglish (US)
Pages (from-to)1278-1280
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume143
Issue number10
DOIs
StatePublished - 2019

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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