Cadaveric renal transplantation at the University of Pittsburgh: a two and one-half-year experience with the point system.

R. Shapiro, A. G. Tzakis, T. R. Hakala, W. Lopatin, S. Mitchell, B. Koneru, A. Stieber, R. D. Gordon, T. E. Starzl

Research output: Contribution to journalArticlepeer-review

Abstract

From January 1, 1986 to July 30, 1988, 530 consecutive cadaver kidney transplantations were performed with patient selection by a point system that took into account time awaiting an organ, donor-recipient matching, degree of presensitization, and some less important factors. The effect of the system was to diminish judgmental factors in case selection which in the past, had probably operated to the disadvantage of "undesirable" potential recipients, including older ones. Primary 1-year graft survival (74%) and graft survival after retransplantation (71%) were lower than in the earlier time. However, the results with triple-drug therapy using CsA, AZA and P demonstrated 88% 1-year graft survival for primary graft recipients and 74% in highly sensitized patients, with comparable patient mortality. These latter observations provide some assurance that the concepts of equitable access and efficient utilization of a scarce resource are not mutually exclusive.

Original languageEnglish (US)
Pages (from-to)181-187
Number of pages7
JournalClinical transplants
StatePublished - 1988

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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