Calcium signaling surrounding fertilization in the nematode Caenorhabditis elegans

Gunasekaran Singaravelu, Andrew Singson

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Calcium plays a prominent role during fertilization in many animals. This review focuses on roles of Ca2+ during the events around fertilization in the model organism, Caenorhabditis elegans. Specifically, the role of Ca2+ in sperm, oocytes and the surrounding somatic tissues during fertilization will be discussed, with the focus on sperm activation, meiotic maturation of oocytes, ovulation, sperm-egg interaction and fertilization.

Original languageEnglish (US)
Pages (from-to)2-9
Number of pages8
JournalCell Calcium
Issue number1
StatePublished - Jan 2013

All Science Journal Classification (ASJC) codes

  • Physiology
  • Molecular Biology
  • Cell Biology


  • Calcium wave
  • ITR-1
  • Inositol triphosphate (IP3)
  • Meiotic maturation
  • Membranous organelle (MO)
  • Ovulation
  • SPE-38
  • Sheath cells
  • Spermatheca
  • Spermiogenesis
  • Store operated calcium entry (SOCE)
  • TRP-3/SPE-41


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