Calorimetry of proteins and nucleic acids

G. Eric Plum, Kenneth J. Breslauer

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


The availability of sensitive calorimetric instrumentation has led to a considerable increase in thermodynamic studies of proteins, nucleic acids, and their interactions. This article reviews some of the recent contributions of calorimetry to characterizing the thermodynamic origins of protein and nucleic acid stability and conformational preferences, as well as the interactions of proteins with each other, with small molecules, and with nucleic acids.

Original languageEnglish (US)
Pages (from-to)682-690
Number of pages9
JournalCurrent Opinion in Structural Biology
Issue number5
StatePublished - Oct 1995

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology


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