Campylobacter fetus infections in humans: Exposure and disease

Jaap A. Wagenaar, Marcel A.P. Van Bergen, Martin J. Blaser, Robert V. Tauxe, Diane G. Newell, Jos P.M. Van Putten

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Campylobacter fetus can cause intestinal illness and, occasionally, severe systemic infections. Infections mainly affect persons at higher risk, including elderly and immunocompromised individuals and those with occupational exposure to infected animals. Outbreaks are infrequent but have provided insight into sources. Source attribution of sporadic cases through case-control interviews has not been reported. The reservoirs for C. fetus are mainly cattle and sheep. Products from these animals are suspected as sources for human infections. Campylobacter fetus is rarely isolated from food, albeit selective isolation methods used in food microbiology are not suited for its detection. We hypothesize that the general population is regularly exposed to C. fetus through foods of animal origin, cross-contaminated foodstuffs, and perhaps other, as yet unidentified, routes. Campylobacter fetus infection should be suspected particularly in patients with nonspecific febrile illness who are immunocompromised or who may have been occupationally exposed to ruminants.

Original languageEnglish (US)
Pages (from-to)1579-1586
Number of pages8
JournalClinical Infectious Diseases
Volume58
Issue number11
DOIs
StatePublished - Jun 1 2014

Fingerprint

Campylobacter fetus
Campylobacter Infections
Food Microbiology
Infection
Food
Ruminants
Occupational Exposure
Disease Outbreaks
Sheep
Fever
Interviews
Population

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Keywords

  • Campylobacter fetus
  • Exposure
  • Food safety
  • Immunocompromised

Cite this

Wagenaar, J. A., Van Bergen, M. A. P., Blaser, M. J., Tauxe, R. V., Newell, D. G., & Van Putten, J. P. M. (2014). Campylobacter fetus infections in humans: Exposure and disease. Clinical Infectious Diseases, 58(11), 1579-1586. https://doi.org/10.1093/cid/ciu085
Wagenaar, Jaap A. ; Van Bergen, Marcel A.P. ; Blaser, Martin J. ; Tauxe, Robert V. ; Newell, Diane G. ; Van Putten, Jos P.M. / Campylobacter fetus infections in humans : Exposure and disease. In: Clinical Infectious Diseases. 2014 ; Vol. 58, No. 11. pp. 1579-1586.
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Wagenaar, JA, Van Bergen, MAP, Blaser, MJ, Tauxe, RV, Newell, DG & Van Putten, JPM 2014, 'Campylobacter fetus infections in humans: Exposure and disease', Clinical Infectious Diseases, vol. 58, no. 11, pp. 1579-1586. https://doi.org/10.1093/cid/ciu085

Campylobacter fetus infections in humans : Exposure and disease. / Wagenaar, Jaap A.; Van Bergen, Marcel A.P.; Blaser, Martin J.; Tauxe, Robert V.; Newell, Diane G.; Van Putten, Jos P.M.

In: Clinical Infectious Diseases, Vol. 58, No. 11, 01.06.2014, p. 1579-1586.

Research output: Contribution to journalArticle

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Wagenaar JA, Van Bergen MAP, Blaser MJ, Tauxe RV, Newell DG, Van Putten JPM. Campylobacter fetus infections in humans: Exposure and disease. Clinical Infectious Diseases. 2014 Jun 1;58(11):1579-1586. https://doi.org/10.1093/cid/ciu085