@inbook{47cb18381563490abd86534045762406,
title = "Cell Adhesion, Cellular Tension, and Cell Cycle Control",
abstract = "Cooperative signaling between growth factor receptor tyrosine kinases, integrins, and the actin cytoskeleton is required for activation of the G1-phase cyclin-dependent kinases and progression through G1-phase. Increasing evidence suggests that there is cell type specificity in these cooperative interactions and that the compliance of the underlying substratum can strongly affect adhesion-dependent signaling to the cell cycle. This chapter reviews our current methods for studying how cell type specificity and changes in substratum compliance can contribute to G1-phase cell cycle control. We also describe several of our current analytical procedures.",
author = "Klein, {Eric A.} and Yuval Yung and Paola Castagnino and Devashish Kothapalli and Assoian, {Richard K.}",
note = "Funding Information: We thank the present and former lab colleagues who helped in the development of the methodologies described here. We also thank Paul Janmey and Valerie Weaver for guidance in the development of polyacrylamide gel–matrix protein substrata technology in our lab. Work in our lab is supported by grants from the National Institutes of Health.",
year = "2007",
doi = "10.1016/S0076-6879(07)26008-2",
language = "English (US)",
isbn = "9780123739247",
series = "Methods in Enzymology",
pages = "155--175",
editor = "David Cheresh",
booktitle = "Integrins",
}