TY - JOUR
T1 - Cell Surface Interactions with Concanavalin A
T2 - Determination by Microhemadsorption
AU - Furmanski, Philip
AU - Phillips, Philip G.
AU - Lubin, Martin
N1 - Funding Information:
Supported by U.S. Public Health Service research grant 5 RO1 AI 09288 from the National Institute of Allergy and Infectious Diseases, research grant E-577 from the American Cancer Society, and postdoctoral fellowships DRF-588 (P. F.) and DRF-664 (P.G.P.) from the Damon Runyon Memorial Fund for Cancer Research, Inc. 5 1972 140 1 216 219
PY - 1972/5
Y1 - 1972/5
N2 - A microhemadsorption method is described for measuring the interaction between concanavalin A and single transformed or untransformed cells without removing them from the substrate. When indicator red blood cells were coated with Con A, their adherence to SV3T3 cells was only 2-4-fold greater than to 3T3 cells. On the other hand, when the two cell lines were coated with Con A, there was a very marked difference in the ability of the lectin on each to adsorb uncoated red cells.
AB - A microhemadsorption method is described for measuring the interaction between concanavalin A and single transformed or untransformed cells without removing them from the substrate. When indicator red blood cells were coated with Con A, their adherence to SV3T3 cells was only 2-4-fold greater than to 3T3 cells. On the other hand, when the two cell lines were coated with Con A, there was a very marked difference in the ability of the lectin on each to adsorb uncoated red cells.
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U2 - 10.3181/00379727-140-36429
DO - 10.3181/00379727-140-36429
M3 - Article
C2 - 5064199
AN - SCOPUS:0015338289
SN - 0037-9727
VL - 140
SP - 216
EP - 219
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 1
ER -