Chemistry and bioactivity of Gardenia jasminoides

Wenping Xiao, Shiming Li, Siyu Wang, Chi Tang Ho

Research output: Contribution to journalReview articlepeer-review

68 Scopus citations

Abstract

Gardenia jasminoides, grown in multiple regions in China, was commonly used as a natural yellow dye but has been one of the popular traditional Chinese medicines since the discovery of its biological property a few decades ago. It has been reported that G. jasminoides possess multiple biological activities, such as antioxidant properties, hypoglycemic effect, inhibition of inflammation, antidepression activity, and improved sleeping quality. In this review, our aim was to have a comprehensive summary of its phytochemistry including the extraction, isolation, and characterization of volatiles and bioactive molecules in G. jasminoides, focusing on the two major phytochemicals, genipin and crocin, which possess potent medicinal properties. Furthermore, this study attempted to establish a structure–activity relationship between the two major series of molecules with two pharmcophores and their biological activities, which would serve further exploration of the properties of phytocompounds in G. jasminoides as potential functional foods and medicines.

Original languageEnglish (US)
Pages (from-to)43-61
Number of pages19
JournalJournal of Food and Drug Analysis
Volume25
Issue number1
DOIs
StatePublished - Jan 1 2017

All Science Journal Classification (ASJC) codes

  • Food Science
  • Pharmacology

Keywords

  • Gardenia jasminoides
  • crocin
  • genipin
  • geniposide
  • iridiod

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