Chemistry and biology of dihydroisoxazole derivatives: Selective inhibitors of human transglutaminase 2

Keyphrases

• 4,5-Dihydroisoxazoles 33%
• Active Sites 16%
• Biological Systems 16%
• Bromo 16%
• Cancer Types 16%
• Carmustine 16%
• Celiac Sprue 16%
• Dihydroisoxazole 100%
• Endocytosis 16%
• Glioblastoma multiforme 16%
• Glutathione 16%
• Halo 16%
• HCT116 Cells 16%
• High Specificity 16%
• Human Disease 16%
• Intestinal Tissue 16%
• Kinh 16%
• Low Toxicity 16%
• Microscopic Visualization 16%
• Nitrosourea 16%
• Nucleophilic 16%
• Oral Bioavailability 16%
• Pharmacodynamic Properties 16%
• Pharmacokinetic Properties 16%
• Selective Inhibition 16%
• Selective Inhibitor 100%
• Serum Half-life 16%
• Small Intestine 16%
• Synergism 16%
• Thiols 16%
• Tissue Toxicity 16%
• Transglutaminase 2 100%
• Warhead 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Bioavailability 16%
• Carmustine 33%
• Coeliac Disease 16%
• Diseases 16%
• Glioblastoma 16%
• Glutathione 16%
• Neoplasm 16%
• Nitrosourea 16%
• Pharmacodynamics 16%
• Pharmacokinetics 16%
• Protein Glutamine Gamma Glutamyltransferase 2 100%
• Synergism 16%
• Thiol 16%