Chromatin complexes regulating gene expression in Drosophila

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91 Scopus citations


Polycomb-group proteins form chromatin complexes at target genes such as Ubx, providing a cellular memory of gene activity in early development and determining the later activity of the gene. The complexes, whose constituents vary depending on site and genomic context, initiate at specific sites, but can extend to involve larger chromatin domains. How they persist through cell proliferation and how they silence gene activity are still open issues.

Original languageEnglish (US)
Pages (from-to)466-472
Number of pages7
JournalCurrent Opinion in Genetics and Development
Issue number4
StatePublished - Aug 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology


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