TY - JOUR
T1 - Chromatin complexes regulating gene expression in Drosophila
AU - Pirrotta, Vincenzo
N1 - Funding Information:
I am grateful to C Tatout and B Horard for discussions and criticism. Apologies are due to many whose important contributions could not be adequately treated because of space limitations. This work was supported by a grant from the Swiss National Science Foundation.
PY - 1995/8
Y1 - 1995/8
N2 - Polycomb-group proteins form chromatin complexes at target genes such as Ubx, providing a cellular memory of gene activity in early development and determining the later activity of the gene. The complexes, whose constituents vary depending on site and genomic context, initiate at specific sites, but can extend to involve larger chromatin domains. How they persist through cell proliferation and how they silence gene activity are still open issues.
AB - Polycomb-group proteins form chromatin complexes at target genes such as Ubx, providing a cellular memory of gene activity in early development and determining the later activity of the gene. The complexes, whose constituents vary depending on site and genomic context, initiate at specific sites, but can extend to involve larger chromatin domains. How they persist through cell proliferation and how they silence gene activity are still open issues.
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U2 - 10.1016/0959-437X(95)90050-Q
DO - 10.1016/0959-437X(95)90050-Q
M3 - Article
C2 - 7580138
AN - SCOPUS:0029100039
SN - 0959-437X
VL - 5
SP - 466
EP - 472
JO - Current Opinion in Genetics and Development
JF - Current Opinion in Genetics and Development
IS - 4
ER -