Chromosome size-dependent control of meiotic recombination

David B. Kaback; Vincent Guacci; Dianna Barber; James W. Mahon

doi:10.1126/science.1566070

Chromosome size-dependent control of meiotic recombination

David B. Kaback, Vincent Guacci, Dianna Barber, James W. Mahon

NJMS-Molecular Core

Research output: Contribution to journal › Article › peer-review

121 Scopus citations

Abstract

Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.

Original language	English (US)
Pages (from-to)	228-232
Number of pages	5
Journal	Science
Volume	256
Issue number	5054
DOIs	https://doi.org/10.1126/science.1566070
State	Published - 1992

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title = "Chromosome size-dependent control of meiotic recombination",

abstract = "Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.",

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year = "1992",

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AU - Guacci, Vincent

AU - Barber, Dianna

AU - Mahon, James W.

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AB - Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.

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Chromosome size-dependent control of meiotic recombination

Abstract

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