Chromosome size-dependent control of meiotic recombination

David B. Kaback, Vincent Guacci, Dianna Barber, James W. Mahon

Research output: Contribution to journalArticlepeer-review

121 Scopus citations


Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.

Original languageEnglish (US)
Pages (from-to)228-232
Number of pages5
Issue number5054
StatePublished - 1992

All Science Journal Classification (ASJC) codes

  • General

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