Chromosome size-dependent control of meiotic recombination

David B. Kaback, Vincent Guacci, Dianna Barber, James W. Mahon

Research output: Contribution to journalArticlepeer-review

121 Scopus citations

Abstract

Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.

Original languageEnglish (US)
Pages (from-to)228-232
Number of pages5
JournalScience
Volume256
Issue number5054
DOIs
StatePublished - 1992

All Science Journal Classification (ASJC) codes

  • General

Fingerprint Dive into the research topics of 'Chromosome size-dependent control of meiotic recombination'. Together they form a unique fingerprint.

Cite this