Clavicipitic acid, a metabolite of Claviceps strain SD 58, is a mixture of isomers, the major one of which was shown by a single-crystal X-ray analysis to give structure Ha. It is formed from tryptophan and mevalonic acid but is not further converted into the tetracyclic ergot alkaloid elymoclavine. Its formation represents a derailment of ergoline biosynthesis after the first pathway-specific step, the isoprenylation of tryptophan.
All Science Journal Classification (ASJC) codes
- Organic Chemistry