Clinical correlation with serum-soluble interleukin-2 receptor levels in guillain-barré syndrome

S. Bansil, F. A. Mithen, S. D. Cook, A. Sheffet, Christine Rohowsky-Kochan

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

In patients with Guillain-Barré syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.

Original languageEnglish (US)
Pages (from-to)1302-1305
Number of pages4
JournalNeurology
Volume41
Issue number8
StatePublished - Jan 1 1991

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this