Clinical failure of vancomycin in a dialysis patient with methicillin-susceptible vancomycin-heteroresistant S. aureus

Dahlene N. Fusco, Elizabeth L. Alexander, Scott A. Weisenberg, Jose R. Mediavilla, Barry N. Kreiswirth, Audrey N. Schuetz, Stephen G. Jenkins, Kyu Y. Rhee

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

We report a case of recurrent Staphylococcus aureus bacteremia in a patient who failed vancomycin due to a vancomycin-heteroresistant strain lacking methicillin resistance. Although initial isolates were susceptible, isolates obtained after vancomycin chemotherapy were vancomycin heteroresistant. This case thus illustrates the clinical emergence of vancomycin heteroresistance.

Original languageEnglish (US)
Pages (from-to)180-183
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume65
Issue number2
DOIs
StatePublished - Oct 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Keywords

  • Failure
  • Heteroresistance
  • Staphylococcus aureus
  • Vancomycin

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